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南昌地区某院就诊患者γ-干扰素释放试验的应用价值研究
Study on Application Value of Interferon-γ Release Assay in Patients in a Hospital in Nanchang
【摘要】 目的 了解江西省南昌地区某院就诊患者γ-干扰素释放试验(IGRA)检测结核分枝杆菌潜伏感染流行病学特征。方法 收集江西省南昌地区某院2017年1月至2020年12月来院就诊的2561例患者血液,用γ干扰素释放试验检测患者潜在感染状况。结果 就诊患者IGRA阳性率为39.55%(1013/2561),不同年份患者之间IGRA阳性率比较,差异无统计学意义(χ~2=4.775,P>0.05),不同性别、不同年龄组患者之间IGRA阳性率比较,差异有统计学意义(χ~2=9.442,χ~2=18.487,均P<0.05)。结论 南昌地区某院就诊患者结核杆菌潜伏感染相对较高,提示应加强人员监测力度,提高结核分枝杆菌潜伏感染的早期诊断率。
【Abstract】 Objective Studying epidemiological features of latent infection of mycobacterium tuberculosis on the basis of Interferon-γ Release Assay(IGRA) in patients in a hospital in Nanchang. Methods Collecting blood from 2561 patients who visited a hospital in Nanchang, Jiangxi Province from January 2017 to December 2020; detecting the potential infection status of patients by IGRA. Results The IGRA positivity rate of patients visiting the hospital was 39.55%(1013/2561); no statistical difference was discovered in the IGRA positivity rate among patients of different years,(χ~2=4.775, P>0.05). statistical difference was discovered in the IGRA positivity rate among patients of different genders and age groups (χ~2=9.442,χ~2=18.487,P<0.05). Conclusion A relatively high incidence of latent infection of Mycobacterium tuberculosis is observed in a hospital in Nanchang. This result suggests that health surveillance of residents should be strengthened to improve the early diagnosis of latent infection of Mycobacterium tuberculosis.
【Key words】 Interferon-γ Release Assay(IGRA); Tuberculosis(TB); Latent infection of tuberculosis;
- 【文献出处】 江西医药 ,Jiangxi Medical Journal , 编辑部邮箱 ,2023年03期
- 【分类号】R52;R446.6
- 【下载频次】12