【摘要】 目的 观察iFlow彩色血流编码成像技术用于评价腔内治疗急性下肢缺血（ALLI）效果的价值。方法 回顾性分析17例接受腔内治疗的ALLI患者。腔内治疗前对患肢行数字减影血管造影（DSA）,后于DSA引导下行机械血栓清除，并留置导管行接触性溶栓治疗，必要时行球囊扩张及支架植入术；腔内治疗后再次行患肢DSA。记录治疗前后患肢踝肱指数（ABI）。以iFlow技术对腔内治疗前后DSA影像行后处理获得iFlow图像，测量股骨头、膝关节及踝关节区达峰时间（TTP）,计算膝关节区与股骨头区TTP差值（即膝关节区域TTP差值）、踝关节区与膝关节区的TTP差值（即踝关节区域TTP差值）,比较治疗前后TTP及TTP差值的差异，分析治疗前后ABI变化（△ABI）与踝关节区TTP变化(△TTP_踝关节)的相关性。结果 17例均完成腔内治疗，2例因患侧血管腔内残留血栓而接受截肢。治疗后膝关节及踝关节区域TTP较前缩短、TTP差值较前缩小而ABI较前升高（P均<0.05）,股骨头区TTP与治疗前差异无统计学意义（P>0.05）。△ABI与△TTP_踝关节呈正相关（r=0.551,P<0.05）。结论 iFlow技术可用于评估腔内治疗ALLI效果。更多还原

【Abstract】 Objective To explore the value of iFlow color flow coding imaging technology for evaluating the effect of endovascular treatment of acute lower limb ischemia（ALLI）. Methods Data of 17 patients with clinically diagnosed ALLI who underwent endovascular treatment were retrospectively analyzed. Digital subtraction angiography（DSA） of the affected limb was performed before endoluminal treatment, followed by DSA-guided mechanical thrombi removal and contact thrombolysis through indwelling catheter, and then balloon dilation and stent implantation were performed if necessary, and DSA of the affected limb was performed again after endoluminal treatment. The ankle brachial index（ABI） of the affected limb before and after treatment were recorded. iFlow images were obtained using post-processing of DSA images before and after endoluminal treatment. The time to peak（TTP） of femoral head, knee and ankle regions were measured, respectively, and differences of TTP between the knee region and femoral head region（denoted as knee region TTP difference）, also of ankle region and knee region（denoted as ankle region TTP difference） were calculated. TTP and TTP were compared before and after treatment, and the correlation of ABI before and after treatment（△ABI） and changes of ankle region TTP(△TTP_ankle) were analyzed. Results All 17 patients completed endovascular treatment, among them 2 underwent amputation treatment for residual thrombi in the affected side after treatment. After treatment, TTP of knee and ankle region became shorter than before, TTP differences of knee and ankle regions were smaller, while ABI were higher than those before（all P<0.05）, but TTP difference of femoral head region was not significantly different from that before treatment（P>0.05）. △ABI was moderately positive correlated with △TTP_ankle（r=0.551, P<0.05）. Conclusion iFlow technology could be used to evaluate the effect of endovascular treatment of ALLI.更多还原