【摘要】 目的：探究超声引导下星状神经节阻滞(SGB)对妇科腹腔镜术后应激反应及康复的影响。方法：选择2021年1月-2022年11月于本院妇产科行妇科腹腔镜手术患者140例，随机分为观察组及对照组各70例，分别给予超声引导下SGB或星状神经节处注射等量生理盐水。比较分析两组手术前后外周血肿瘤坏死因子α(TNF-α)、白细胞介素6(IL-6)、IL-8、IL-10、疼痛视觉模拟评分(VAS)及术后首次排气(尿)时间及排尿量。结果：观察组术后20min及24h外周血IL-6、IL-8、TNF-α水平低于对照组，IL-10水平高于对照组；术后20min VAS(3.26±1.35分)低于对照组(5.63±1.42分);术后肛门首次排气时间(6.73±1.52h)、拔除尿管后首次排尿时间(0.97±0.16h)均早于对照组(9.67±2.04h、1.75±0.73h),首次排尿量(0.24±0.06L)大于对照组(0.11±0.03L),总不良反应(20.0%)低于对照组(42.9%)(均P<0.05)。结论：超声引导下的SGB在妇科腔镜术后对患者应激反应控制及康复均有积极作用，且用药安全。更多还原

【Abstract】 Objective: To study the effects of ultrasound-guided stellate ganglion block(SGB) during gynecological laparoscopic surgery of patients on their postoperative stress response and rehabilitation. Methods: A total of 140 patients who wanted laparoscopic gynecological surgery were selected and were divided into two groups(70 cases in per group) from January 2021 to November 2022. The patients in the observation group were given ultrasound-guided SGB during surgery, and the patients in the control group were injected with saline at the stellate ganglion as a placebo. The levels of tumor necrosis factor α(TNF-α), interleukin 6(IL-6), IL-8, IL-10, and visual analogue scale(VAS) score before and after surgery, the time of the first exhaust(urine output) after surgery, and the first urine output volume of the patients were compared between the two groups. Results: The levels of IL-6, IL-8, and TNF-α in peripheral blood of the patients in the observation group at 20min and 24h after surgery were significantly lower than those of the patients in the control group. The level of IL-10 of the patients in the observation group was significantly higher than that of the patients in the control group. The VAS score at 20 minutes after surgery(3.26±1.35 points) of the patients in the observation group was significantly lower than that(5.63±1.42 points) of the patients in the control group. The time of the first exhaust after surgery(6.73±1.52 h) and the time of the first urine output after catheter removal(0.97±0.16 h) of the patients in the observation group were significantly earlier than those(9.67±2.04 h and 1.75±0.73 h) of the patients in the control group. The first urination output volume(0.24±0.06 L) of the patients in the observation group was significantly higher than that(0.11±0.03 L) of the patients in the control group. The total adverse reactions rate(42.9%) of the patients in the observation group was significantly lower than that(20.0%) of the patients in the control group(all P<0.05).Conclusion:Ultrasound-guided SGB used during gynecological laparoscopic surgery of the patients has very positive effect on their postoperative stress control and rehabilitation,and with the safety of medicine.更多还原