【摘要】 目的 分析在牙周炎所致前牙扇形移位治疗中对患者采取正畸联合牙周夹板治疗的临床效果。方法方便选取2018年1月—2020年6月期间广饶县人民医院收治的78例牙周炎所致前牙扇形移位患者为研究对象，随机（黑白球方式）分为对照组（牙周夹板+基础牙周治疗，39例）与观察组（牙周夹板+基础牙周治疗+正畸，39例），两组均治疗12个月，比较分析两组治疗后的临床疗效、龈沟液炎症因子[前列腺素E2(PGE2)、细胞间粘附分子-1(sICAM)、蛋白激活激酶5(PAK5)]水平、牙周治疗效果（菌斑指数、探诊深度、牙龈指数、附着丧失水平）、牙周袋深度、前牙覆盖度、牙槽骨高度。结果 治疗后，观察组临床疗效94.9%高于对照组74.3%，差异有统计学意义（χ~2=6.303,P<0.05）。观察组龈沟液炎症因子水平低于对照组，差异有统计学意义（P<0.05）。观察组牙周治疗效果（菌斑指数、探诊深度、牙龈指数、附着丧失水平）低于对照组，差异有统计学意义（P<0.05）。观察组牙周袋深度、前牙覆盖度、牙槽骨高度均低于对照组，差异有统计学意义（P<0.05）。结论 在牙周炎所致前牙扇形移位疾病治疗过程中，用正畸与牙周夹板联合治疗的治疗效果较好，联合治疗下牙周夹板能够帮助改善牙周状态，并维持牙周组织正常生理功能，而正畸治疗则能纠正由于牙周疾病引起的移位情况，因此能明显提高治疗效果，并减轻炎症水平，较常规治疗措施更能改善覆盖高度等情况。更多还原

【Abstract】 Objective To analyze the clinical effect of orthodontic treatment combined with periodontal splinting in the treatment of periodontitis-induced scalloped displacement of anterior teeth. Methods 78 patients with periodontitisinduced scalloped displacement of anterior teeth admitted to Guangrao County People’s Hospital from January 2018 to June 2020 were conveniently selected as the research objects. They were randomly divided into the control group(periodontal splint+basic periodontal treatment, 39 cases) and the observation group(periodontal splint+basic periodontal treatment+orthodontic treatment, 39 cases). Both groups were treated for 12 months. The clinical efficacy gingival crevicular fluid inflammatory factor [prostaglandin E2(PGE2), intercellular adhesion molecule-1(sICAM), protein activated kinase 5(PAK5)] level, periodontal treatment effect(plaque index, probing depth, gingival index, attachment loss level), periodontal pocket depth, anterior tooth coverage, alveolar bone height. Results After treatment, the clinical efficacy of the observation group was 94.9% higher than that of the control group 74.3%, and the difference was statistically significant(χ~2=6.303, P<0.05). The level of inflammatory factors in gingival crevicular fluid in the observation group was lower than that in the control group, and the difference was statistically significant(P<0.05). The periodontal treatment effect(plaque index, probing depth, gingival index, and attachment loss level) of the observation group was lower than that of the control group, and the difference was statistically significant(P<0.05). The depth of periodontal pocket, anterior tooth coverage, and alveolar bone height in the observation group were lower than those in the control group, and the difference was statistically significant(P<0.05).Conclusion During the treatment of periodontitis-induced scalloped displacement of anterior teeth, the treatment effect of combined orthodontic treatment and periodontal splint is better. Under combined treatment, periodontal splint can help improve the periodontal status and maintain the normal physiological function of periodontal tissue, while orthodontic treatment can correct the displacement caused by periodontal disease, so it can significantly improve the treatment effect and reduce the level of inflammation, compared to conventional treatment measures, it can better improve coverage height.更多还原