【摘要】 目的 研究三氧矿物聚合物（mineral trioxide aggregate, MTA）直接盖髓预防年轻恒牙畸形中央尖折断的临床效果。方法 方便选取2020年1月—2022年1月盐城市第三人民医院口腔科收治的年轻恒牙畸形中央尖折断患者72例为研究对象，按治疗方法分组，对照组36例（Dycal直接盖髓法）、观察组36例（MTA直接盖髓法），分析两组恢复情况、牙齿健康状态、炎症反应及整体疗效。结果 观察组的炎症消失与功能恢复时间均短于对照组，治疗后3个月的牙冠根比、牙根管壁厚均优于对照组，差异有统计学意义（P<0.05）。观察组治疗后3个月的GI、SBI、PLI、POS、PTV、VAS评分均低于对照组，差异有统计学意义（P<0.05）。观察组在治疗后的IL-6、IL-10、TNF-α、CRP水平均低于对照组，差异有统计学意义（P<0.05）。观察组的治疗有效率（91.67%）、一次修补与充填成功率（88.89%）明显高于对照组的72.22%、69.44%，而观察组折断率为2.78%显著低于对照组的22.22%，差异有统计学意义（χ~2=4.600、4.126、4.571,P<0.05）。结论 以MTA直接盖髓干预年轻恒牙畸形中央尖折断患者疗效显著，可迅速改善炎症并促其康复，对维持牙齿健康状态有重要意义。更多还原

【Abstract】 Objective To study the clinical effect of mineral trioxide aggregate(MTA) direct capping pulp to prevent central cusp fracture in young permanent malocclusion. Methods 72 young patients with central cusp fracture of permanent tooth deformities admitted to the Stomatology Department of Yancheng Third People’s Hospital from January 2020 to January 2022 were conveniently selected as the research subjects. They were divided into two groups according to treatment methods: a control group of 36 cases(Dycal direct pulp capping method) and an observation group of 36 cases(MTA direct pulp capping method). The recovery status, dental health status, inflammatory response, and overall efficacy of the two groups were analyzed. Results The inflammation disappearance and functional recovery time of the observation group were shorter than those of the control group, and the crown root ratio and root canal wall thickness of the teeth were better than those of the control group at 3 months after treatment, the difference was statistically significant(P<0.05). After 3 months of treatment, the GI, SBI, PLI, POS, PTV, and VAS scores of the observation group were lower than those of the control group, and the difference was statistically significant(P<0.05). IL-6,IL-10, TNF-α, CRP levels in the observation group after treatment were all lower than those of the control group, the difference was statistically significant(P<0.05). The effective rate of treatment(91.67%) and the success rate of one-time repair and filling(88.89%) in the observation group were significantly higher than those in the control group(72.22% and 69.44%, while the fracture rate of the observation group(2.78%) was significantly lower than that of the control group(22.22%), the difference was statistically significant(χ~2=4.600, 4.126, 4.571, P<0.05). Conclusion The direct pulp capping with MTA has a significant therapeutic effect on young patients with central cusp fracture of permanent teeth, which can quickly improve inflammation and promote recovery, and is of great significance for maintaining dental health.更多还原