【摘要】 目的 探讨自拟中药方联合穴位贴敷、中药保留灌肠治疗慢性肾脏病（chronic kidney disease, CKD）3～5期患者的临床疗效。方法 随机选取2020年4月—2022年4月新沂市中医医院收治的60例CKD 3～5期的患者为研究对象，采用随机数表法分为两组，各30例，对照组实施基础治疗，观察组在对照组基础上实施自拟中药方联合穴位贴敷、中药保留灌肠。对比两组治疗有效率、治疗前后SCr和BUN水平。结果 观察组总有效率为90.0%(27/30)，高于对照组的66.7%(20/30)，差异有统计学意义（χ~2=4.812,P<0.05）。治疗后，观察组SCr、BUN水平低于对照组，差异有统计学意义（t=3.771、2.792,P<0.05）。结论 在CKD患者的治疗中应用中医综合治疗技术，能够提高疗效，降低SCr及BUN水平，从而利于改善患者的临床症状和生活质量。更多还原

【Abstract】 Objective To explore the clinical efficacy of self-made Chinese medicine prescription combined with acupoint application and Chinese medicine retention enema in the treatment of patients with chronic kidney disease(Chronic Kidney Disease, CKD) stage 3-5. Methods Sixty patients with stage 3 to 5 CKD treated in Xinyi Hospital of Traditional Chinese Medicine from April 2020 to April 2022 were random selected as the study objects, and were divided into two groups with 30 cases in each group by random number table method. The control group received basic treatment, and the observation group received self-designed Chinese prescription combined with acupoint application and TCM retention enema on the basis of the control group. The effective rate and SCr and BUN levels before and after treatment were compared between the two groups. Results Observation group total effective rate was 90.0%(27/30), higher than that of control group 66.7%(20/30), the difference was statistically significant(χ~2=4.812, P<0.05). After treatment, SCr and BUN levels in the observation group were lower than those in the control group, and the difference was statistically significant(t=3.771, 2.792, P<0.05). Conclusion The application of TCM comprehensive treatment technology in the treatment of CKD patients can improve the curative effect, reduce the level of SCr and BUN,and thus improve the clinical symptoms and quality of life of patients.更多还原