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角膜共焦显微镜检查与角膜刮片检查在真菌性角膜炎诊断中的对比分析

Comparison of corneal confocal microscopy and corneal scraping in the diagnosis of fungal keratitis

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【作者】 赵烨宋丹梁明刘娟

【Author】 ZHAO Ye;SONG Dan;LIANG Ming;LIU Juan;Operating Room of Ear, Nose and Throat, The First Affiliated Hospital of Harbin Medical University;

【通讯作者】 刘娟;

【机构】 哈尔滨医科大学附属第一医院五官科手术室

【摘要】 目的 探讨角膜共焦显微镜检查与角膜刮片检查在真菌性角膜炎患者诊断中的价值。方法 选取2022年2月~2022年7月在我院诊治的角膜炎患者73例(73只眼),分别行角膜共焦显微镜检查和角膜刮片检查,对比分析2种检查方法的阳性检出率。结果 73只眼中,确诊为真菌性角膜炎者43例,其中,角膜共焦显微镜检查阳性30眼,检出率为69.77%;角膜刮片检查阳性20眼,实验室检出率为46.51%,两种方法的阳性检出率比较,差异有统计学意义(P=0.029)。结论 角膜共焦显微镜检查具有非侵入性的优势,可以帮助确定受累深度,将角膜刮片检查与角膜共焦显微镜检查相结合,对提高真菌性角膜炎患者的诊断率具有重要意义。

【Abstract】 Objective To explore the value of corneal confocal microscopy and corneal scraping examination in the diagnosis of fungal keratitis. Methods Seventy-three patients(73 eyes) with keratitis diagnosed and treated in our hospital from February 2022 to July 2022 were selected for corneal confocal microscopy and corneal scraping, respectively, the positive detection rates of the two methods were compared and analyzed. Results Among 73 eyes, 43 eyes were diagnosed as fungal keratitis, of which, the corneal confocal microscopy was positive in 30 eyes, with a detection rate of 69.77%; 20 eyes were positive by corneal scraping, and the laboratory detection rate was 46.51%; the difference was statistically significant(P=0.029). Conclusion Corneal confocal microscopy has the advantage of non-invasive and could help determine the depth of involvement of the lesion. The combination of corneal scraping and corneal confocal microscopy is of great significance in improving the diagnostic rate of fungal keratitis.

  • 【文献出处】 哈尔滨医科大学学报 ,Journal of Harbin Medical University , 编辑部邮箱 ,2023年04期
  • 【分类号】R772.21
  • 【下载频次】10
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