【摘要】 考察催化剂、溶剂、溴化试剂、温度和时间对SalenMn(Ⅲ)催化的非活性烯烃溴胺化反应的反应产率和对映体过量(ee)值的影响。研究表明，当1为催化剂、氯代苯为溶剂和次溴酸钠为溴化试剂在10℃下反应6h,反应产率最高为88%,ee(对映体过量值)最高为97%。此方法为构建手性氮杂环化合物提供了新选择。更多还原

【Abstract】 The bromoamination of unactive olefin catalyzed by SalenMn(Ⅲ) chiral ligand was studied. The effects of catalyst, solvent, bromine source, temperature and time on the reaction yield and enantioselectivity were investigated. It was found that when Cat.1 is used as catalyst, chlorobenzene as solvent and sodium hypobromate as brominating agent, the reaction is conducted at 10℃ for 6 h, the yield of the product is up to 88%, and the enantiomeric excess(ee) value is 97%. This method provides a new choice for the construction of chiral nitrogen heterocyclic compounds.更多还原