【摘要】 本论文设计合成了基于1,3-二氨基胍盐酸盐、氨基胍盐酸盐的新型香豆素类荧光探针L1、L2。通过紫外-可见、荧光光谱的变化研究探针L1、L2对金属离子的识别效应。利用Job’s plot曲线确定探针L1与Co²⁺形成了1∶2的配合物，探针L2和Fe³⁺形成了3∶1的配合物，且表现为明显的荧光增强。探针L1对Co²⁺的检出限可达到10^-6mol/L,探针L2对Fe³⁺的检出限可达到10^-7mol/L。两种高灵敏度荧光探针有望应用于生物和环境监测领域。更多还原

【Abstract】 The fluorescent probe has important application value in biomedicine,explosives detection and environmental science. In this paper,two novel fluorescence-enhanced probes based on coumarin and guanidine were synthesized and characterized. In DMF solution, probe L1 （bis（ 7-diethylamino-coumarin-3-yl）-1,3-diaminoguanidine） shows highly selective and sensitive fluorescence enhancement detection of Co²⁺with the binding ratio of1 ∶ 2( L1 ∶ Co²⁺) and the LOD of 1. 03 × 10^-6 mol/L. In DMSO solution, probe L2（3-aminoguanidine-（ 7-diethylamino-coumarin）） shows a highly selective and sensitive fluorescence enhancement detection of Fe³⁺ with the binding ratio of 3 ∶ 1( L2 ∶ Fe³⁺) and the LOD of 5. 77 × 10^-7 mol/L. Two highly sensitive fluorescent probes are expected to be used in the field of organism and environmental monitoring.更多还原