【摘要】 目的 ：探究益血生联合铁剂治疗妊娠期缺铁性贫血对铁代谢指标、红细胞相关指标及母婴结局的影响。方法 ：采用随机数字表法将2020年4月―2022年4月300例妊娠期缺铁性贫血患者分为三组（铁剂组、益血生组及联合组），铁剂组给予铁剂治疗，益血生组给予益血生治疗，联合组给予铁剂与益血生联合治疗，所有患者及新生儿均随访至妊娠结束后3个月。比较三组治疗疗效、新生儿生长发育情况及治疗前后铁代谢指标、红细胞指标。结果 ：联合组治疗总有效率高于铁剂组、益血生组；联合组治疗后血清铁蛋白（SF）、铁（SI）水平及铁蛋白饱和度（TSAT）高于铁剂组、益血生组，且铁剂组高于益血生组；联合组治疗后血红蛋白（HGB）、平均红细胞体积（MCV）、平均红细胞血红蛋白量（MCH）、平均红细胞血红蛋白浓度（MCHC）高于铁剂组、益血生组；联合组婴儿出生时的体重重于铁剂组、益血生组；联合组脐血SF水平高于铁剂组、益血生组，且益血生组高于铁剂组。联合组母婴不良妊娠结局低于铁剂组、益血生组。结论 ：益血生联合铁剂治疗妊娠期缺铁性贫血的有效率较高，可改善铁代谢及红细胞功能，减轻贫血程度，促进胎儿生长发育，减少不良妊娠结局。更多还原

【Abstract】 Objective To explore the effects of Yixuesheng capsule combined with iron supplement in the treatment of iron deficiency anemia during pregnancy on iron metabolism indexes, red blood cell-related indexes and maternal-infant outcomes.Methods 300 patients with iron deficiency anemia during pregnancy from April 2020 to April 2022 were divided into three groups(iron supplement group, Yixuesheng capsule group and combined group) by the random number table method. The iron supplement group was given iron supplement treatment, and the Yixuesheng capsule was treated with Yixuesheng capsule, and the combined group was given iron supplement combined with Yixuesheng capsule. All patients and neonates were followed up until 3 months after the end of pregnancy. The therapeutic efficacy, neonatal growth and development as well as iron metabolism indexes and red blood cell indexes before and after treatment were compared among the three groups. Results The total effective rate of treatment in combined group was higher than that in iron supplement group and Yixuesheng capsule group. Serum ferritin, iron level and ferritin saturation after treatment in combined group were higher than those in iron supplement group and Yixuesheng capsule group, and the above indexes in iron supplement group were higher than those in Yixuesheng capsule group. The hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration after treatment were higher in combined group than those in iron supplement group and Yixuesheng capsule group. The birth weight at birth was heavier in combined group than that in iron supplement group and Yixuesheng capsule group. The incidence rate of adverse maternal-infant pregnancy outcomes in combined group was lower compared with that in iron supplement group and Yixuesheng capsule group(4.00% vs 14.00%, 12.00%). Conclusion Yixuesheng capsule combined with iron supplement has high effective rate in the treatment of iron deficiency anemia during pregnancy, and it can improve the iron metabolism and red blood cell function, relieve the degree of anemia, promote the fetal growth and development, and lower the adverse pregnancy outcomes.更多还原