【摘要】 水杉（Metasequoia glyptostroboides Hu et Cheng）叶风干粉碎后用甲醇提取，利用硅胶柱层析、MCI柱层析、Sephadex LH-20凝胶柱层析及HPLC等分离技术对其化学成分进行分离纯化，得到6个化合物，经波谱解析和对其理化性质进行对比，鉴定为1个降木脂素和5个木脂素，分别是salicifoliol (1)、lariciresinol 9′-benzoate (2)、（-）-hinokinin (3)、meridinol (4)、8-hydroxypluviatolide(5)和（-）-matairesinol (6)。化合物1、2、5为首次从该植物中分离得到。更多还原

【Abstract】 Metasequoia glyptostroboides leaves were extracted with methanol after air drying and crushing, and their chemical constituents were separated and purified by silica gel column chromatography, MCI column chromatography, Sephadex LH-20 gel column chromatography and HPLC, and 6 compounds were obtained, which were identified by spectroscopic analysis and their physicochemical properties as one norlignans and 5 lignans. Their structures were elucidated as salicifoliol(1), lariciresinol 9’-benzoate(2),(-)-hinokinin(3), meridinol(4), 8-hydroxypluviatolide(5), and(-)-matairesinol(6) respectively. Lignans 1, 2 and 5 were isolated from the plant for the first time.更多还原