【摘要】 目的:探讨实时组织超声弹性成像(RTE)在乳腺癌诊断中的应用价值。方法:选取2019年7至2022年7月在我院就诊的乳腺肿块患者105例，170个病灶，均给予RTE检查，比较良恶性病变RTE参数差异，以及不同临床病理特征恶性病变RTE参数，同时分析弹性评分、整体应变率比值(ESR)、局部应变率比值(LSR)和区域性缺损面积百分比(AREA%)判断良恶性病变的价值。结果:170个病灶，经病理诊断：良性病变70个，恶性病变100个；恶性病变ESR、LSR和AREA%分别为(3.05±0.88)、(46.69±20.28)和(74.30±28.31)%,明显高于良性病变(P<0.05);恶性病变弹性评分≥3分的比例为68.00%,高于良性病变(P<0.05);乳腺纤维瘤和其他类型良性病变弹性评分、ESR、LSR及AREA%比较差异无统计学意义(P>0.05);不同年龄、病灶大小及病理类型恶性病变弹性评分、ESR、LSR及AREA%比较差异无统计学意义(P>0.05);TNM分期Ⅲ～Ⅳ期病灶ESR、LSR及AREA%明显高于Ⅰ～Ⅱ期(P<0.05);弹性评分、ESR、LSR和AREA%判断病变良恶性病变的ROC曲线下面积分别为0.676(95%CI:0.593～0.759)、0.746(95%CI:0.652～0.804)、0.905(95%CI:0.753～0.901)和0.794(95%CI:0.705～0.883),P<0.05。结论:RTE参数在乳腺癌诊断中有一定的应用价值，可提供客观诊断指标，值得临床应用。更多还原

【Abstract】 Objective:To explore the value of real-time tissue ultrasound elastography(RTE) in the diagnosis of breast cancer.Methods:From July 2019 to July 2022,105 patients with breast masses in our hospital with 170 lesions were examined by RTE to compare the differences of RTE parameters between benign and malignant lesions, and RTE parameters of malignant lesions with different clinicopathological characteristics, the values of elasticity score, entirety strain rate ratio(ESR),local strain rate ratio(LSR) and blue area ratio(AREA%) in diagnosing benign and malignant lesions were also analyzed.Results:170 lesions were diagnosed by pathology, including 70 benign lesions and 100malignant lesions.Compared with benign lesions, the ESR,LSR and AREA% of malignant lesions were(3.05 ± 0.88),(46.69 ± 20.28) and(74.30 ± 28.31)%,which were significantly higher(P<0.05); compared with benign lesions, the proportion of elasticity score ≥ 3 in malignant lesions was 67.86%,which was higher than that in benign lesions(P<0.05); there was no significant difference in elastic score, ESR,LSR and AREA% between breast fibroma and other benign lesions(P>0.05); there was no significant difference in elastic score, ESR,LSR and AREA% among patients with different age, lesion size and pathological type(P>0.05); ESR,LSR and AREA% in TNM stage Ⅲ～Ⅳ were significantly higher than those in stage Ⅰ～Ⅱ(P<0.05); the area under the ROC curve of elasticity score, ESR,LSR,and AREA%to judge benign and malignant lesions were 0.676(95%CI:0.593～0.759),0.746(95%CI:0.652～0.804),0.905(95%CI:0.753～0.901) and 0.794(95%CI:0.705～0.883),P<0.05. Conclusion:RTE parameters have a certain application value in the diagnosis of breast cancer, which can provide objective diagnostic indicators and is worth clinical application.更多还原