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抗生素佐剂在治疗鲍曼不动杆菌感染中的研究进展
Research Progress of Antibiotic Adjuvants in the Treatment of Acinetobacter baumannii Infection
【摘要】 目前鲍曼不动杆菌感染治疗困难与多重耐药、广泛耐药菌株的出现以及革兰阴性菌新型抗菌药物缺乏有关。为了治疗和控制鲍曼不动杆菌严重感染,新的用药选择不可或缺。佐剂通过增效抗生素,逆转耐药,克服了现有药物治疗的局限性。本文将可增敏鲍曼不动杆菌的抗生素佐剂加以汇总,拟为临床防治相关感染提供理论依据。
【Abstract】 At present, the difficulties in the treatment of Acinetobacter baumannii infection are related to the emergence of multidrug-resistant bacteria and extensively drug-resistant bacteria, as well as the lack of new antibiotics for Gram-negative bacteria. Therefore, it is necessary to make new drug choices for the treatment and control of serious Acinetobacter baumannii infection. Adjuvants have the ability to overcome the drawbacks of current drug therapy by sensitizing antibiotics and reversing drug resistance. In order to provide a theoretical foundation for the practical prevention and treatment of associated illnesses, this paper describes the antibiotic adjuvants that boost the antibacterial activity against Acinetobacter baumannii.
【Key words】 Acinetobacter baumannii; antibiotic adjuvant; antibiotics; combined medication; synergistic effect; drug resistance;
- 【文献出处】 国外医药(抗生素分册) ,World Notes on Antibiotics , 编辑部邮箱 ,2023年06期
- 【分类号】R446.5
- 【下载频次】47