【摘要】 目的 探讨电脑康复治疗仪联合超早期强化运动康复对脑卒中患者运动功能及生活质量的影响。方法 选取首都医科大学附属北京潞河医院2017年6月至2020年9月收治的150例脑卒中患者，分为观察组(67例)与对照组(74例)。对照组实施电脑康复治疗仪治疗，观察组患者在对照组基础上联合超早期强化运动康复治疗。比较2组患者治疗前后简化Fugl-Meyer量表评分、改良阿什沃思量表评分、Brunnstrom分级、生活质量综合评定问卷、凝血功能[凝血酶原时间(prothrombin time,PT)、凝血酶原活动度(prothrombin activity,PTA)]、血常规及同型半胱氨酸水平。结果 治疗后，观察组患者简化Fugl-Meyer量表评分(75.63±10.84)高于对照组(47.29±8.75)(P<0.05)；改良阿什沃思量表评分(0.57±0.13)低于对照组(1.82±0.25)(P<0.05)。治疗3个月后，观察组患者Ⅰ级、Ⅱ级患者比例均显著低于对照组(P<0.05)；Ⅲ级、Ⅳ级、Ⅴ级患者比例均显著高于对照组(P<0.05)。治疗3个月后，观察组患者生活质量总评分为(73.21±4.98)分，显著优于对照组的(60.37±5.22)分(P<0.05)。治疗3个月后，观察组PTA、白细胞计数、血小板计数、同型半胱氨酸水平均低于对照组(均P<0.05)，而PT和血红蛋白水平高于对照组(均P<0.05)。结论 电脑康复治疗仪联合超早期强化运动康复可改善脑卒中患者的运动功能状态，提升患者的生活质量，改善患者的凝血功能。[国际神经病学神经外科学杂志,2023,50(4):34-39]更多还原

【Abstract】 Objective To investigate the effect of computer rehabilitation therapeutic apparatus combined with ultraearly intensive exercise rehabilitation on motor function and quality of life in patients with stroke.Methods A total of 150patients with stroke who were admitted to Beijing Luhe Hospital Affiliated to Capital Medical University,from June 2017 to September 2020 were selected and divided into observation group with 67 patients and control group with 74 patients.The patients in the control group received treatment with a computer rehabilitation therapeutic apparatus,and those in the observation group received ultra-early intensive exercise rehabilitation therapy in addition to the treatment in the control group.The two groups were compared in terms of simplified Fugl-Meyer Assessment(FMA) score,modified Ashworth score,Brunnstrom stage,General Quality of Life Inventory,coagulation function [prothrombin time(PT) and prothrombin time activity(PTA)],routine blood test results,and homocysteine level before and after treatment.Results After treatment,compared with the control group,the observation group had a significantly higher simplified FMA score(75.63±10.84 vs 47.29±8.75,P<0.05) and a significantly lower modified Ashworth score(0.57±0.13 vs 1.82±0.25,P<0.05).After 3 months of treatment,compared with the control group,the observation group had a significantly higher proportion of patients with grade Ⅰ/Ⅱ disease(P<0.05) and a significantly lower proportion of patients with grade Ⅲ/Ⅳ/Ⅴ disease(P<0.05).After 3 months of treatment,the observation group had a significantly better total quality of life score than the control group(73.21±4.98 vs 60.37±5.22,P<0.05).After 3 months of treatment,compared with the control group,the observation group had significantly lower PTA level,white blood cell count,platelet count,and homocysteine level(P<0.05) and significantly higher levels of PT and hemoglobin(P<0.05).Conclusions Computer rehabilitation therapeutic apparatus combined with ultra-early intensive exercise rehabilitation can improve the motor function,quality of life,and coagulation function in patients with stroke.[Journal of International Neurology and Neurosurgery,2023,50(4):34-39]更多还原