【摘要】 目的 探讨应用低剖面可视化腔内支撑装置（LVIS）治疗症状性大脑中动脉狭窄的安全性和有效性。方法 分析2018年6月—2021年6月广东省中山市人民医院脑血管介入科应用LVIS治疗有完整随访资料的症状性大脑中动脉狭窄患者23例。记录手术成功率、并发症发生情况及支架内再狭窄情况，平均随访6～32个月。结果 23例患者均成功释放支架，术后1例出现远隔部位再灌注出血，经积极保守治疗后好转。1例出现支架内血栓，经抽吸血栓后稍好转。1例仍有短暂性脑缺血发作，造影复查发现支架内再狭窄，通过球囊扩张血管成形，效果良好。术前和术后的狭窄率及NIHSS评分比较，差异有统计学意义（P<0.05）。结论 应用LVIS治疗症状性大脑中动脉狭窄可行、有效。[国际神经病学神经外科学杂志, 2023, 50(2):44-48]更多还原

【Abstract】 Objective To investigate the safety and efficacy of low-profile visualized intraluminal support(LVIS) stent in the treatment of symptomatic middle cerebral artery stenosis. Methods A retrospective analysis was performed for 23patients with symptomatic middle cerebral artery stenosis who were treated with LVIS stent in Department of Cerebrovascular Intervention, Zhongshan City People’s Hospital, from June 2018 to June 2021 and had complete follow-up data. The success rate of surgery, complications, and in-stent restenosis were recorded, and the patients were followed up for 6-32months. Results The stents were successfully released in all 23 patients. Among these patients, 1 patient developed distant reperfusion bleeding after surgery and was improved after active conservative treatment; 1 patient had stent thrombosis and was improved after aspiration; 1 patient still had transient ischemic attack with in-stent restenosis found by angiography and had a good outcome after balloon dilatation angioplasty. There were significant changes in stenosis rate and National Institutes of Health Stroke Scale score after surgery(P <0.05). Conclusions LVIS stent is feasible and effective in the treatment of symptomatic middle cerebral artery stenosis. [Journal of International Neurology and Neurosurgery, 2023, 50(2):44-48]更多还原