【摘要】 目的：分析刘国安教授治疗冠心病的用药规律。方法：收集2020年10月1日至2021年10月1日甘肃省中医院刘国安名中医工作室门诊诊治的114例冠心病患者的病案信息，描述性分析用药频数、性味等用药情况，对高频用药进行聚类分析、因子分析。结果：114首处方共涉及中药72味，频数≥30次的中药有18味，前3味依次为甘草、瓜蒌、薤白。药性多为平、温性，其次为寒性和微寒性。药味多为甘，其次为苦、辛。高频药物因子分析得出4个公因子，主要涉及麦冬、五味子、瓜蒌、薤白、半夏、茯苓、甘草等7味中药。高频药物聚类分析得到6类：第1类为瓜蒌、薤白、桂枝、丹参、枳实；第2类为麦冬、五味子、人参、酸枣仁、石菖蒲、三七粉、水蛭；3类为半夏、茯苓、远志；其余3类为单味药，分别是甘草、山药、川芎。结论：刘国安教授认为冠心病多因气阴两虚，气机不畅，血瘀受阻所致，用药以补气养阴、行气除痹及活血祛瘀为主，体现了寓通于补，通补兼施的治疗思想。更多还原

【Abstract】 Objective: To analyze medication rules of professor Liu Guoan’s treatment of coronary heart disease(CHD). Methods: Medical records information of 114 CHD patients diagnosed and treated in professor Liu Guoan’s famous TCM doctor’s outpatient of Gansu provincial hospital of TCM were collected between October 1st, 2020 and October 1st, 2021, to carry out descriptive analysis of drug use frequency, nature and property, and to perform cluster analysis and factor analysis of high frequency medicine. Results: There are 72 herbs involved in 114 prescriptions, 18 herbs with the frequency≥30 times, the top three herbs are Gancao(Glycyrrhizae radix et Rhizoma), Gualou(Trichosanthis fructus) and Xiebai(Allii macrostemonis bulbus). The nature of the medicine is mild and warm, the next cold and slight cold, the flavor of the drug is sweet mostly, the next bitter and pungent.Four common factors are obtained by factor analysis of high-frequency medicine, mainly including Maidong(Ophiopogonis radix), Wuweizi(Schisandrae chinensis Fructus), Gualou, Xiebai, Banxia(Pinelliae Rhizoma),Fuling(poria) and Gancao. By cluster analysis of high-frequency medicine, six categories contain: the first category including Gualou, Xiebai, Guizhi, Danshen and Zhishi; the second category including Maidong(ophiopogonis radix), Wuweizi(schisandrae chinensis fructus), ginseng, Suanzaoren(ziziphi spinosae semen), Shichangpu(ziziphi spinosae semen), Sanqi(notoginseng radix et rhizoma) powder, Shuizhi(hirudo); the third category involving Banxia, Fuling and Yuanzhi; the remaining three categories belong to single herb, referring to Gancao, Shanyao(dioscoreae rhizoma) and Chuanxiong(Chuanxiong Rhizoma) respectively. Conclusion: Professor Liu Guoan considers that CHD is induced by deficiency of Qi and yin, impeded Qi movement, and obstruction caused by blood stasis, mainly administering the medicine of tonifying Qi and nourishing Yin, promoting Qi circulation to remove arthralgia, activating blood to eliminate the stasis, which embodies his therapeutic thinking of finding dredging in tonifying, both unobstructing and tonifying.更多还原