【摘要】 目的 探讨改进清洁消毒方法对烧伤整形病房耐碳青霉烯类肠杆菌目细菌(CRE)的防控及消毒效果。方法 选取某院2021年2月1日—8月31日烧伤整形科住院的297例患者作为对照组，将2021年9月1日—2022年2月28日采取改进清洁消毒方法后住院的210例患者作为干预组，统计、比较干预前后患者CRE检出率、医院感染发生率及环境CRE检出率。结果 干预组患者医院感染发病率、CRE检出率分别为0.95%、0,分别低于对照组的4.04%、2.02%(均P<0.05)。干预组空气微生物学、物体表面微生物学、ATP生物荧光、荧光标记检测的合格率均较对照组上升(χ~2值分别为5.52、13.08、6.66、15.01,均P<0.05)。结论 改进清洁消毒方法能降低烧伤病房医院感染发病率和CRE检出率，提升环境物体表面的清洁度，改善医院感染防控效果。更多还原

【Abstract】 Objective To explore the effect of improving cleaning and disinfection methods on the prevention, control and disinfection of carbapenem-resistant Enterobacterales(CRE) in burn plastic surgery ward. Methods 297 patients who admitted to the department of burn plastic surgery in a hospital from February 1 to August 31, 2021 were selected as the control group, and 210 patients who admitted to the hospital from September 1, 2021 to February 28, 2022 after cleaning and disinfection methods improved were selected as the intervention group. Detection rate of CRE from patients, incidence of healthcare-associated infection(HAI) with CRE, and detection rate of environmental CRE before and after intervention were statistically analyzed and compared. Results The incidence of HAI and detection rate of CRE from patients in the intervention group were 0.95% and 0, respectively, lower than 4.04% and 2.02% in the control group(both P<0.05). Compared to the control group, qualified rates of detection of air and surface microbiology, adenosine triphosphate(ATP) bioflorescence and fluorescence labeling in the intervention group were all higher(χ~2=5.52, 13.08, 6.66, and 15.01, respectively, all P<0.05). Conclusion Improving cleaning and disinfection method can reduce the incidence of HAI and the detection rate of CRE in burn wards, improve the surface cleanliness of environmental objects, as well as the effectiveness of HAI prevention and control.更多还原