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乳管镜下庆大霉素联合地塞米松乳管灌注治疗乳管扩张性病变68例临床分析

Clinical analysis of 68 cases of mammary duct dilatation treated with mammary duct perfusion gentamicin combined with dexamethasone under ductoscopy

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【作者】 贺丽芳; 杨婵萍; 陈泽晓; 吴俊东;

【Author】 HE Li-fang;YANG Chan-ping;CHEN Ze-xiao;WU Jun-dong;The Breast Center, Cancer Hospital of Shantou University Medical College;Guangdong Provincial Key Laboratory for Breast Cancer Diagnosis &Treatment;The Operating Room, Cancer Hospital of Shantou University Medical College;

【通讯作者】 吴俊东;

【机构】 汕头大学医学院附属肿瘤医院乳腺中心; 广东省乳腺癌诊治研究重点实验室; 汕头大学医学院附属肿瘤医院手术室;

【摘要】 目的:探讨乳管镜下庆大霉素联合地塞米松乳管灌注治疗乳管扩张性病变的临床应用价值。方法:回顾性分析2015年7月至2021年3月在我院门诊行乳管镜下庆大霉素联合地塞米松乳管灌注治疗的68例乳管扩张性病变患者的临床资料。结果:59例经灌注治疗治愈,治愈率为86.8%,8例好转,好转率11.8%,1例无效。结论:乳管镜下联合药物灌注治疗集乳管检查及治疗于一体,疗效明确,治愈率高,能使大部分乳管扩张性病变患者避免长期服药和手术。

【Abstract】 Objective : To explore the clinical value of gentamicin combined with dexamethasone in the treatment of mammary duct dilatation. Methods : The clinical data of 68 patients with mammary duct dilatation treated with gentamicin combined with dexamethasone mammary duct perfusion under ductoscopy from July 2015 to March 2021 were analyzed retrospectively. Results : A total of 59 cases were cured by perfusion treatment, the cure rate was 86. 8%; 8 cases were improved, the improvement rate was 11. 8%, and 1 case was ineffective. Conclusion : Ductoscopy combined with drug perfusion therapy integrates breast duct examination and treatment has obvious curative effect, high cure rate; no need for hospitalization, no surgical scar, rapid recovery and short course of treatment. It is simple and easy to operate. This method can make most patients with breast duct dilatation free from surgery and long-term medication.

【基金】 广东省科技专项基金(“大专项+任务清单”)项目(210728156901648)
  • 【文献出处】 赣南医学院学报 ,Journal of Gannan Medical University , 编辑部邮箱 ,2023年03期
  • 【分类号】R655.8
  • 【下载频次】20
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