【摘要】 蜱虫是一类专性吸血的外寄生虫，需要吸取大量血液维持生活史循环。吸血不仅引起宿主的炎症反应，同时也是传播病原体的过程，危害人类健康，影响畜牧业，造成公共卫生负担。硬蜱的各个生活史与血餐息息相关，但目前对于硬蜱吸血的生理生化过程以及其携带的病原体之间的相互作用知之甚少。伴随着血餐的摄取，硬蜱在生理生化上发生巨大的改变，包含溶血反应、胞内消化、蛋白质降解等，携带的病原体也需要适应血餐引起的独特的生理生化的变化，如摄取血餐、消化等，才能在蜱虫中繁殖，以便在硬蜱再次血餐时通过唾液传播到新的宿主。本文总结了硬蜱血餐过程中中肠的生理生化过程，阐述了血餐与硬蜱生活史的关系，为蜱传疾病的防控提供支持。更多还原

【Abstract】 Ticks are bloodsucking ectoparasites that not only consume a large amount of blood and cause host damage,but also transmit various pathogens,seriously endangering human and animal health and affecting economic development. Different stage of life cycles of hard ticks are closely related to their blood meal,but little is known about relationships between hard ticks and the pathogens. During the blood meal,the physiology and biochemistry of hard ticks have undergone tremendous changes,including hemolysis,intracellular digestion,protein degradation and other processes. This process is also a critical period for the spread and proliferation of pathogens. Tick borne pathogens must adapt to the life cycle of hard ticks and physiological changes,before they were transmitted to new hosts when the hard tick sucks again. This paper focused on the physiological and biochemical processes of the midgut during the blood meal,elaborating the relationship between blood meal and hard tick life cycle,which benefit to the prevention and control of tick borne diseases.更多还原