【摘要】 选取一例椎动脉起始部狭窄患者的术前CT图像，通过逆向建模方法得到术前几何并对其进行虚拟手术，获得具有不同支架扩张率(1.0、1.05和1.1)的介入治疗术后模型，采用计算流体力学方法获取虚拟支架植入术后椎动脉内血流动力学参数分布并分析支架扩张率对支架植入段的血流动力学影响。研究发现，椎动脉起始部的血流速度随着支架扩张率的增大明显减小，椎动脉出口流量随着支架扩张率的增加而增大。血流动力学参数表明支架植入段内高危区域(低TAWSS、高OSI和高RRT区域)集中出现在右侧。随着支架扩张率的增大，高危区域逐渐扩大并分为上下两部分，其中上部圆形区逐渐上移，下部条形区逐渐向右下侧扩散。研究结果可为此类手术的评价和优化提供血流动力学参考。更多还原

【Abstract】 In this paper, the preoperative Computed Tomography(CT) images of a patient with stenosis at the origin of the vertebral artery was selected, and the preoperative geometry was obtained by inverse modeling method. Virtual surgery was performed to obtain postintervention models with different stent expansion ratios(1.0, 1.05, and 1.1). We used the hydrodynamic method to obtain the distribution of hemodynamic parameters in the vertebral artery after virtual stent implantation,and analyzed the influence of stent expansion rate on the hemodynamics of the stent implantation segment. The study found that the blood flow velocity at the origin of the vertebral artery decreased significantly with increasing stent expansion rate, and the vertebral artery outlet flow increased with increasing stent expansion rate. The high-risk areas(low TAWSS, high OSI and high RRT areas)in the stent implantation segment concentrated on the right side. As the expansion rate of the stent increases, the high-risk area gradually expands and is divided into upper and lower parts, in which the upper circular area gradually moves upward, and the lower strip area gradually spreads to the lower right. The research results can provide hemodynamic reference for the evaluation and optimization of such operations.更多还原