【摘要】 目的:观察内镜黏膜下剥离术(ESD)治疗结直肠早癌及癌前病变的疗效。方法:将60例结直肠早癌及癌前病变患者随机分为观察组和对照组，每组30例。观察组患者采用ESD治疗，对照组患者采用内镜下黏膜切除术(EMR)治疗，比较2组患者手术指标、手术切除情况及术后并发症发生情况。结果:观察组患者手术时间、标本直径均长于对照组(P<0.05),术中出血量、标本厚度均多于对照组(P<0.05);观察组患者整体切除、完全切除率高于对照组(P<0.05),不完全切除率低于对照组(P<0.05);观察组患者术后并发症发生率低于对照组(P<0.05)。结论:ESD治疗结直肠早癌及癌前病变可减少术后并发症的发生，提高病变组织切除率。更多还原

【Abstract】 Objective To observe the effect of endoscopic submucosal dissection(ESD) in the treatment of early colorectal cancer and precancerous lesion. Methods Randomy divided 60 patients treated in author’s hospital with ESD for their early colorectal cancer and precancerous lesion into observation group(30 cases, received ESD) and control group(30 cases, EMR,i.e endoscopic mucosal resection);then, compared both groups’ operative norms, the status on operatively resected, and postoperative complication incidence. Results In operating time and the specimen diameter, in intraoperative bleeding volume and specimen thickness, in the ratio of whole resection and complete resection, in the ratio of incomplete resection, as well as in the incidence of postoperative complication, observation group was respectively longer, more, higher, lower, as well as lower than control group(all, P<0.05). Conclusion ESD for early colorectal cancer and precancerous lesion can reduce postoperative complication, and enhance the ratio of lesion tissue resected.更多还原