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中国子宫颈癌筛查指南(一)

Guidelines for cervical cancer screening in China

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【作者】 李明珠魏丽惠隋龙马丁孔北华吴小华吴鹏乔友林赵方辉王临虹

【Author】 Chinese Society for Colposcopy and Cervical Pathology of China Healthy Birth Science Association;Chinese Society of Gynecologic oncology, Chinese Medical Association;Chinese Gynecological Cancer Society;Branch of Women’s Health Medicine of China International Exchange and Promotive Association for Medical and Health Care;National Cervical Cancer Prevention Consortium of Cancer Foundation of China;Branch of Cancer Prevention and Control, Chinese Preventive Medicine Association;Chinese Association for Maternal and Child Health Studies;

【通讯作者】 魏丽惠;马丁;孔北华;

【机构】 中国优生科学协会阴道镜和子宫颈病理学分会中华医学会妇科肿瘤学分会中国抗癌协会妇科肿瘤专业委员会中国医疗保健国际交流促进会妇产健康医学分会中国癌症基金会全国子宫颈癌防治协作组中华预防医学会肿瘤预防与控制专委会中国妇幼健康研究会子宫颈癌防控研究专业委员会北京大学人民医院复旦大学附属妇产科医院华中科技大学同济医学院附属同济医院山东大学齐鲁医院复旦大学附属肿瘤医院北京协和医学院群医学及公共卫生学院中国医学科学院肿瘤医院中国疾病预防控制中心

【摘要】 结合我国子宫颈上皮内病变和子宫颈癌发病情况,以及全球筛查策略,为实现消除子宫颈癌的目标,我国七个学(协)会专家共同制定了子宫颈癌筛查指南。本指南推荐高危型HPV核酸检测作为子宫颈癌的初筛方法,并采用经国内外权威机构认可、经临床验证可用于初筛的HPV核酸检测方法和试剂。子宫颈细胞学筛查用于不具备HPV核酸检测条件的地区,当条件成熟后,采用基于HPV核酸检测的筛查方法。联合筛查用于医疗卫生资源充足地区、机会性筛查人群以及部分特殊人群女性的子宫颈癌筛查。25岁女性为筛查起始年龄,25~64岁女性,采用每5年一次的HPV核酸单独检测/联合筛查;或每3年一次细胞学检查。65岁以上女性,如既往有充分的阴性筛查记录,可终止筛查。对不同特殊人群提出相应的筛查方案。

【Abstract】 In response to the incidence of cervical intraepithelial neoplasia and cervical cancer in China and global screening strategies, a collaborative effort was undertaken by seven Chinese medical societies to develop this guideline for cervical cancer screening. The guideline recommends high-risk human papillomavirus(hr-HPV) nucleic acid detection as the preferred method for primary screening, which should have been approved by authoritative institutions and clinically validated for primary screening. In areas without access to HPV nucleic acid testing, cytology can be used as an alternative. However, it is recommended to replace cytology with HPV-based screening as conditions permit. Cotesting(HPV testing in combination with cytology) is recommended for areas with sufficient medical resources, opportunistic screening populations, and partial special populations. The guideline recommends that individuals with a cervix initiate cervical cancer screening at age 25 years and undergo HPV testing alone or cotesting every five years, or cytology alone every three years. Women over the age of 65 who have had documented adequate negative prior screening in the past may discontinue screening. Corresponding screening programs are proposed for different special populations. The development of these guidelines is an important step in the effort to eliminate cervical cancer in China.

【关键词】 子宫颈癌初次筛查方法方案指南
【Key words】 cervical cancerprimary screeningmethodprogramguideline
【基金】 国家重点研发计划(2021YFC2701202)
  • 【文献出处】 中国妇产科临床杂志 ,Chinese Journal of Clinical Obstetrics and Gynecology , 编辑部邮箱 ,2023年04期
  • 【分类号】R737.33
  • 【下载频次】137
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