【摘要】 目的 探讨新疆喀什地区变应性鼻炎（AR）患者变应原的种类及差异性，为其治疗及预防提供研究依据。方法分析喀什第一人民医院于2015年7月～2020年12月确诊的AR患者资料，分析其血清特异性免疫球蛋白E(specific IgE,sIgE)检测结果，按性别、民族、年龄分组，分析各组变应原的差异。结果 528例AR患者sIgE检测结果中屋尘螨/粉尘螨阳性率最高，为246例（46.6%），其后依次为鸡蛋、点青霉/烟曲霉/交链孢霉等。男女之间狗上皮变应原阳性率差异有统计学意义（P<0.05)，不同年龄组间西红柿变应原阳性率差异有统计学意义，而不同民族间变应原阳性率差异无统计学意义。结论屋尘螨/粉尘螨、鸡蛋、点青霉/烟曲霉/交链孢霉为喀什地区AR患者最主要的变应原。更多还原

【Abstract】 OBJECTIVE To investigate the types and differences of allergens in patients with allergic rhinitis(AR in Kashgar, Xinjiang, and to provide a research basis for its treatment and prevention. METHODS A retrospective analysis was conducted on the data of AR patients diagnosed in the First People’s Hospital of Kashgar from July 2015 to December 2020. The specific IgE(sIgE) results of peripheral venous blood and the types of allergens were analyzed. The patients were grouped according to gender, ethnicity and age, and the differences in allergens among the groups were further analyzed.RESULTS Among the sIgE test results of 528 AR patients, the highest positive rate was for dust mites(246 cases, 46.6%),followed by egg, Alternaria alternata/Aspergillus fumigatus/Cladosporium herbarum and so on. There was a statistically significant difference in the dog epithelium allergen positive rate between males and females(P <0.05), and a statistically significant difference in the positive rate of tomato allergen detection among different age groups, while there was no statistically significant difference in the allergen positive rate among different ethnic groups. CONCLUSION Dust mites,egg, and Alternaria alternata/Aspergillus fumigatus/Cladosporium herbarum are the most common allergens in patients with AR in Kashgar.更多还原