【摘要】 目的 比较调强放疗与二维放疗在乳腺癌根治术后应用的安全性。方法 选取2019年3月至2021年6月在河南省人民医院治疗的74例乳腺癌根治术后患者的临床资料，按照随机数字表法分为常规组与研究组，每组37例。常规组予以二维放疗，研究组予以调强放疗。比较两组心脏受照剂量、肌钙蛋白水平、心功能、不良反应。结果 研究组心脏指数V30、V40、V50低于常规组(P<0.05)。放疗5周后，研究组肌钙蛋白水平低于常规组(P<0.05)。放疗5周后，研究组左室舒张末期内径、左房收缩末期内径水平低于常规组(P<0.05)。研究组不良反应发生率为8.11%(3/37),低于常规组[29.73%(11/37)],差异有统计学意义(P<0.05)。结论 调强放疗在乳腺癌根治术后应用安全性较高。更多还原

【Abstract】 Objective To compare the safety of intensity modulated radiotherapy and two-dimensional radiotherapy for breast cancer patients after radical mastectomy. Methods From March 2019 to June 2021, 74 breast cancer patients after radical mastectomy in Henan Provincial People’s Hospital were selected and randomly divided into study group and routine group, with 37 cases in each group. The conventional group received two dimensional radiotherapy, and the study group received intensity modulated radiotherapy. The cardiac dose, troponin level, cardiac function and adverse reactions were compared between the two groups. Results The heart indexes V30, V40 and V50 of the study group were lower than those of the conventional group(P<0.05). After 5 weeks of radiotherapy, the level of troponin in the study group was lower than that in the conventional group(P<0.05). After 5 weeks of radiotherapy, the left ventricular end-diastolic diameter(LVDd) and left atrial end-systolic diameter(LADs) levels in the study group were lower than those in the conventional group(P<0.05). The incidence of adverse reactions in the study group(8.11%,3/37) was lower than that in the conventional group(29.73%,11/37,P<0.05). Conclusions Intensity modulated radiotherapy is safe for breast cancer patients after radical mastectomy.更多还原