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基于STM32的生物电阻抗测量系统的设计与应用

Design and Application of a Bioelectrical Impedance Measurement System Based on STM32

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【作者】 李曙王直滕凯李想

【Author】 LI Shu;WANG Zhi;TENG Kai;LI Xiang;School of Electronic Information,Jiangsu University of Science and Technology;Department of Blood Transfusion,Zhenjiang Fourth People’s Hospital;School of Computer Science,Jiangsu University of Science and Technology;

【机构】 江苏科技大学电子信息学院镇江第四人民医院输血科江苏科技大学计算机学院

【摘要】 为了更好地了解患者的血凝病理状况,方便医生及时用药,基于STM32和AD5933设计了一种血凝电阻抗测量系统。使用该系统测量标准电阻、电容构成的RC并联网络,与TH2832LCR电桥仪对比,误差小于0.9%;进行标准电阻的扫频测量,误差小于0.5%。提出一种凝血因子反应时间R检测方法,对40组血样进行测量,并与实际R值对比,误差均小于4%;使用等浓度差的CaCl2溶液与多组枸橼酸钠抗凝血混合,发现随着CaCl2溶液浓度以0.025mol/L微量减小,R明显增大,符合生物学规律;在不同条件下对多组血样进行测量,误差均小于5%。结果表明该电阻抗测量系统可以用于凝血因子反应时间的检测,且具有较高的精度、灵敏度和较好的重复性、重现性。

【Abstract】 In order to better understand the blood coagulation pathological status of patients,facilifating doctors to timely adjust medication,a bioelectrical impedance measurement system based on STM32 and AD5933 is designed.This system is used to measure the RC parallel network composed of standard resistance and capacitance,compared with TH2832 LCR bridge meter,the error is less than0.9%.The sweep frequency measurement of the standard resistance is performed,and the error is less than 0.5%.A method for detecting blood coagulation factor reaction time of R is proposed,and 40 groups of blood samples are measured.Compared with the actual R value,the error is less than 4%.CaCl2 solutions of equal concentration difference are mixed with multiple groups of sodium citrate anticoagulate blood,it is found that as the concentration of CaCl2 solution decreases slightly by 0.025 mol/L,R increases significantly,which conforms to the laws of biology.Multiple groups of blood samples are measured under different conditions,the error is less than5%.The results indicate that the electrical impedance measurement system can be used for the detection of coagulation factor reaction time with high accuracy and sensitivity and good repeatability and reproducibility.

【基金】 国家自然科学基金项目(51875270)
  • 【文献出处】 电子器件 ,Chinese Journal of Electron Devices , 编辑部邮箱 ,2023年01期
  • 【分类号】R319;TP368.1
  • 【下载频次】114
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