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噬菌体治疗在畜牧业中的应用

Phage Therapy and Its Application in Animal Husbandry

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【作者】 文英; 谭俊; 马梦真; 袁修磊; 何博; 常建军; 马文涛;

【Author】 WEN Ying;TAN Jun;MA Meng-zhen;YUAN Xiu-lei;HE Bo;CHANG Jian-jun;MA Wen-tao;College of Agriculture and Animal Husbandry,Qinghai University;Animal Husbandry and Aquatic Technology Promotion Service Center of Pingluo County;College of Veterinary Medicine,Northwest A&F University;

【通讯作者】 常建军;马文涛;

【机构】 青海大学农牧学院; 平罗县畜牧水产技术推广服务中心; 西北农林科技大学动物医学院;

【摘要】 细菌对抗生素产生耐药性的问题日益严重,并且新型抗生素研发困难,在此情况下,人们迫切需要一种新型的治疗剂替代抗生素对细菌病进行防治。噬菌体逐步回到人们的视野,噬菌体具有种类多、特异性强、安全性高以及成本低廉等优点,人们对于噬菌体的研究也逐渐深入,噬菌体治疗在畜牧行业甚至是人类临床上都发挥了重要作用。论文综述了噬菌体治疗的发展过程,介绍了噬菌体的给药途径以及噬菌体治疗在畜牧行业中的应用,为噬菌体的研究及其未来在畜牧行业中的应用提供参考。

【Abstract】 The problem of bacterial resistance to antibiotics is becoming more and more serious, and it is difficult to develop new antibiotics.In this case, people urgently need a new kind of therapeutic agent to replace antibiotics for the prevention and treatment of bacterial diseases.Phage, which can be seen everywhere in nature, has gradually returned to people’s field of vision.Phage has many advantages, such as variety, high specificity, strong safety and low cost, and people’s research on phage has gradually deepened.Phage therapy has played a role in animal husbandry industry and even in human clinical practice.This paper briefly describes the development process of phage therapy, introduces the drug delivery routes and the application of phage therapy in animal husbandry industry, and provides some reference for the future use of phages in animal husbandry industry.

【关键词】 噬菌体; 治疗; 细菌病; 抗生素; 畜牧;
【Key words】 phages therapy; bacterial infection; antibiotics; animal husbandry;
【基金】 青海省重点研发与转化计划-科技援青项目(2021-QY-211)
  • 【文献出处】 动物医学进展 ,Progress in Veterinary Medicine , 编辑部邮箱 ,2023年12期
  • 【分类号】S854
  • 【下载频次】121
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