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黄河三角洲地区结直肠无蒂锯齿状病变的临床病理特征

Clinicopathological features of sessile serrated colorectal lesions in the Yellow River Delta

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【作者】 王娜; 贾兴芳; 王凯; 郝佳慧; 储琳琳; 刘成霞;

【Author】 WANG Na;JIA Xingfang;WANG Kai;HAO Jiahui;CHU Linlin;LIU Chengxia;Department of Gastroenterology,Binzhou Medical University Hospital;

【通讯作者】 刘成霞;

【机构】 滨州医学院附属医院消化内科;

【摘要】 目的 探讨黄河三角洲地区结直肠无蒂锯齿状病变(SSLs)的临床、内镜、病理特征。方法 回顾性分析病理诊断为SSLs的205例患者的临床、内镜、病理资料,包括无蒂锯齿状病变不伴异型增生(SSL-ND)167例,无蒂锯齿状病变伴异型增生(SSL-D)38例。结果 205例患者共273枚病变,SSL-ND共167例,SSL-D共38例,男性多于女性。SSL-ND及SSL-D均以单发多见,多发于右半结肠,SSL-D组直径大于SSL-ND组,P<0.05。两组病变内镜形态比较,P<0.05。结论 锯齿状病变作为结直肠癌重要的癌前病变之一,其中SSLs具有独特的自身表现,发生细胞异型增生比例高,需准确掌握其临床、内镜及病理学特征,提高检出率。

【Abstract】 Objective To investigate the clinical, endoscopic and pathological features of sessile serrated colorectal lesions(SSLs) in the Yellow River Delta.Methods The clinical, endoscopic and pathological data of 205 patients with pathologically diagnosed SSLs were retrospectively analyzed, including 167 cases of sessile serrated lesions without dysplasia(SSL-ND) and 38 cases of sessile serrated lesions with dysplasia(SSL-D).Results There were 273 lesions found in 205 patients, including 167 cases of SSL-ND and 38 cases of SSL-D, with more males than females. Both SSL-ND and SSL-D were single, mostly in the right colon. The diameter of the SSL-D group was larger than that of the SSL-ND group, and the difference was statistically significant(P<0.05). The endoscopic morphology of the two groups was statistically significant(P<0.05).Conclusion Serrated lesions are one of the important precancerous lesions of colorectal cancer, in which SSLs have unique self manifestations and a high proportion of cell dysplasia, so it is necessary to accurately grasp their clinical, endoscopic and pathological characteristics to improve the detection rate.

【基金】 山东省教育厅“临床医学+X”学科建设项目(200375);山东省省级临床重点学科建设项目(SLCZDZK-13);滨州市科技发展计划(2015ZC0319)
  • 【文献出处】 滨州医学院学报 ,Journal of Binzhou Medical University , 编辑部邮箱 ,2023年03期
  • 【分类号】R735.34
  • 【下载频次】9
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