节点文献
痰湿理论的源流及其在非酒精性脂肪性肝病中的应用研究进展
Origin of phlegm-damp theory and application research progress of phlegm-damp theory in the treatment of non-alcoholic fatty liver disease
【摘要】 非酒精性脂肪性肝病(NAFLD)属于中医“肝癖”“胁痛”及“积聚”范畴,痰湿是其核心致病因素,贯穿NAFLD病理进展的始终。文章梳理了中医痰湿理论的历史沿革,结合研究进展归纳了NAFLD中痰湿的形成与过食肥甘、过劳伤气、肝脾失调、肾精不足、痰湿体质密切相关,综述了NAFLD痰湿证在肝脏影像学、血清脂质和炎症因子、肠道菌群及胆汁酸代谢等方面不同于其他证型的特点,以及针对NAFLD中“痰湿”的祛湿化痰、疏肝健脾、补肾化痰的治法方药与针刺,以期为中医药治疗NAFLD提供科学支撑。
【Abstract】 Non-alcoholic fatty liver disease(NAFLD) is recognized as ‘hepatomania’ ‘hypochondriac pain’ or ‘abdominal mass’ in traditional Chinese medicine, of which the core pathogenic factor is phlegm damp. The original understanding of theory of phlegm-damp is summarized in this review paper, as well as the research progress in the etiology and pathogenesis such as overeating fat and sweet, overwork, liver and spleen disorder, kidney essence deficiency, phlegm and damp constitution. This paper summarizes the characteristics of phlegm damp syndrome of NAFLD different from other syndrome types in liver imaging,serum lipids and inflammatory factors, intestinal flora and bile acid metabolism, etc., and the treatment methods and prescriptions and acupuncture for eliminating damp and eliminating phlegm, soothing liver and strengthening spleen, and tonifying kidney and eliminating phlegm aiming at ‘phlegm-damp’ in NAFLD, in order to provide scientific support for the treatment of NAFLD with traditional Chinese medicine.
【Key words】 Non-alcoholic fatty liver disease(NAFLD); Phlegm-damp; Eliminating damp and eliminating phlegm; Soothing liver and strengthening spleen; Tonifying kidney and eliminating phlegm;
- 【文献出处】 中华中医药杂志 ,China Journal of Traditional Chinese Medicine and Pharmacy , 编辑部邮箱 ,2023年04期
- 【分类号】R259
- 【下载频次】71