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初诊胃癌患者舌象特征的客观化研究
Objective study on tongue features of newly diagnosed gastric cancer patients
【摘要】 目的:探讨初诊胃癌患者的舌象特点,分析其舌象变化的规律。方法:采用中医人工智能健康状态辨识系统提取301例初诊胃癌患者的舌象特征,探究胃癌患者不同肿瘤特征的舌象特点。结果:胃癌患者不同TNM分期舌色、苔质分布差异有统计学意义(P<0.01),Ⅰ期多见淡红舌,Ⅱ、Ⅲ期多见红绛舌,Ⅳ期多见青紫舌,并随着病情进展,淡红舌逐渐减少,青紫舌逐渐增多;Ⅰ期多见薄苔,Ⅱ、Ⅲ、Ⅳ期多见厚腻苔。肿瘤直径≥5 cm时厚腻苔显著增多(P<0.05),<5 cm时薄苔显著增多(P<0.05);肿瘤标志物CA50>25 ng/mL、CA199>37 ng/mL多见厚腻苔,CA199≤25 ng/mL多见薄腻苔,CA125>35 ng/mL时薄苔显著减少,CEA>5 ng/mL时厚苔显著增多(P<0.05)。结论:不同临床分期的胃癌患者舌色、苔质有所不同;不同肿瘤大小的胃癌患者苔质不同;肿瘤标志物异常升高以厚腻苔为主。
【Abstract】 Objective: To investigate the characteristics of tongue picture of newly diagnosed gastric cancer patients and analyze the regularity of tongue picture changes. Methods: The tongue features of 301 newly diagnosed gastric cancer patients were extracted by the Chinese medicine artificial intelligence health status recognition system, and the tongue features of different tumor features of gastric cancer patients were explored. Results: There was significant difference in tongue color and fur quality among patients with gastric cancer at different TNM stages(P<0.01). Light red tongue was more common in stage I, red tongue was more common in stage I, I I, and cyan was more common in stage IV. Tongue, and with the progress of the disease, the light red tongue gradually decreases, and the blue and purple tongue gradually increases; Thin moss is commonly seen in stage I, and thick greasy moss is commonly seen in stage I, I I and IV. The thick greasy coating increased significantly when the tumor diameter was ≥5 cm(P<0.05), and the thin coating increased significantly when the tumor diameter was <5 cm(P<0.05); The tumor markers CA50>25 ng/mL, CA199>37 ng/mL were mostly thick greasy coating, CA199≤25 ng/mL thin greasy coating,CA125>35 ng/mL thin coating decreased significantly, and CEA>5 ng/mL thick coating increased significantly(P<0.05).Conclusion: The tongue color and fur quality of patients with gastric cancer in different clinical stages are different. The fur quality of patients with gastric cancer in different tumor sizes is different. The abnormal increase of tumor markers is mainly thick and greasy fur.
【Key words】 Gastric cancer; TNM stages; Clinical information; Tongue image; Artificial intelligence;
- 【文献出处】 中华中医药杂志 ,China Journal of Traditional Chinese Medicine and Pharmacy , 编辑部邮箱 ,2023年01期
- 【分类号】R273;R241.25
- 【下载频次】41