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不同年龄段胚胎停育患者中医症状与证素的分布特点

Distribution characteristics of traditional Chinese medicine symptoms and syndrome elements in different age groups of patients with embryo damage

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【作者】 兰萌林雪娟陈杭黄琰钰吴冬梅刘文杰刘艳红

【Author】 LAN Meng;LIN Xue-juan;CHEN Hang;HUANG Yan-yu;WU Dong-mei;LIU Wen-jie;LIU Yan-hong;Research Base of Traditional Chinese Medicine Syndrome, Fujian University of Traditional Chinese Medicine;Key Laboratory of Chinese Medicine Health Status Differentiation of Fujian Province;Collborative Innovation of Health Management of Traditional Chinese Medicine of Fujian Province in 2011;The Second People’s Hospital Affiliated to Fujian University of Traditional Chinese Medicine;Jinjiang Hospital of Traditional Chinese Medicine Affillated to Fujian University of Traditional Chinese Medicine;

【通讯作者】 林雪娟;

【机构】 福建中医药大学中医证研究基地福建省中医健康状态辨识重点实验室福建省2011中医健康管理协同创新中心福建中医药大学附属第二人民医院福建中医药大学附属晋江中医院

【摘要】 目的:探讨不同年龄段胚胎停育患者中医症状与证素的分布特点。方法:以210例胚胎停育患者为研究对象,采用证素辨证方法获取证素及相应积分,分析低、中、高龄3个年龄段胚胎停育患者中医证素分布特点。结果:胚胎停育患者常见的临床表现为乳房胀(经前)、月经夹块、四肢凉、月经量少等;胚胎停育≥2次患者的年龄显著大于胚胎停育1次患者的年龄(P<0.05),且在中龄组和高龄组中的占比升高。低、中、高龄3组患者的病位证素均以肝、胞宫、肾为主,病性证素均以气滞、气虚、阳虚为主。结论:高龄是胚胎停育的重要因素,随年龄的增大胚胎停育风险增高;不同年龄段胚胎停育患者的主要病位均在肝、胞宫、肾,病性均以气滞、气虚、阳虚为主,表现为虚实夹杂的病理状态,肝郁气滞是胚胎停育患者的重要病理特点。

【Abstract】 Objective: To investigate the distribution characteristics of traditional Chinese medicine(TCM) symptoms and syndrome elements in patients with embryo damage in different ages groups. Methods: A total of 210 patients with embryo damage were selected as the research objects. Forensics and corresponding integrals were obtained by syndrome differentiation method to analyze the distribution characteristics of TCM syndrome elements in patients with embryo damage in three ages: low,middle and old. Results: The common clinical manifestations of the patients were breast distension(premenstrual), menstrual cramps, cold limbs, less menstrual volume, etc.. The age of the patients with ≥2 embryo damage was significantly higher than that of the patients with 1 embryo damage(P<0.05), and the proportion of the patients in the middle age group and the elderly group was increased. In the three groups of patients with low, middle and old age, the disease location syndrome elements were mainly liver, cell palace and kidney, and the disease syndrome elements were mainly qi stagnation, qi deficiency and yang deficiency.Conclusion: Old age is an important factor of embryo damage, and the risk of embryo damage increases with the increase of age. The main disease sites of patients with embryo damage in different age groups were liver, cellular palace and kidney, and the diseases were mainly qi stagnation, qi deficiency and yang deficiency. Liver qi stagnation was an important pathological characteristic of patients with embryo damage.

【基金】 国家自然科学基金项目(No.81230087);福建省自然科学基金项目(No.2021J01931)~~
  • 【文献出处】 中华中医药杂志 ,China Journal of Traditional Chinese Medicine and Pharmacy , 编辑部邮箱 ,2023年01期
  • 【分类号】R271.4
  • 【下载频次】28
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