【摘要】 目的:探讨右美托咪定复合罗哌卡因在臂丛神经阻滞中的效果分析。方法:选取武汉中西医结合骨科医院2019年8月—2022年4月就诊的150例上肢骨折患者,随机分为对照组（罗哌卡因麻醉）和观察组（右美托咪定+罗哌卡因麻醉）,每组各75例。对比两组患者麻醉效果、血流动力学指标及不良反应发生情况。结果:与对照组相比,观察组麻醉起效时间（6.62±0.75 min vs 7.89±0.86min）及完全阻滞时间（8.76±0.92 min vs 10.81±1.52 min）均明显缩短,且镇痛维持时间延长（615.67±70.13 min vs 558.39±60.06 min）（均P<0.05）。手术开始后30 min（T2）和手术结束时（T3）,观察组患者的心率（HR）和平均动脉压（MAP）均明显低于对照组（均P<0.05）。两组患者术中不同时刻血氧饱和度（SpO₂）水平无明显差异（均P>0.05）。两组不良反应总发生率比较,观察组明显低于对照组（12.00%vs 29.33%, P<0.05）。结论:右美托咪定复合低浓度罗哌卡因在臂丛神经阻滞中效果显著,复合麻醉起效时间短,血流动力学更稳定,且不良反应发生风险低。更多还原

【Abstract】 Objective: To investigate the effect of dexmedetomidine combined with ropivacaine in brachial plexus block. Methods: A total of 150 patients with upper limb fracture treated in Wuhan Orthopedic Hospital of Integrated Chinese and Western Medicine from August 2019 to April 2022 were randomly divided into the control group（ropivacaine anesthesia） and the observation group（dexmedetomidine+ropivacaine anesthesia）, with 75 cases in each group. Anesthesia effect, hemodynamic indexes and incidence of adverse reactions were compared between the two groups. Results: Compared with the control group, the onset time of anesthesia（6.62±0.75 min vs 7.89±0.86 min） and the complete block time（8.76±0.92 min vs 10.81±1.52 min） in the observation group were significantly shortened, and the duration of analgesia was prolonged（615.67±70.13 min vs 558.39±60.06 min）（all P<0.05）. The heart rate（HR） and mean arterial pressure（MAP） in the observation group were significantly lower than those in the control group at 30 min after operation（T2） and the end of operation（T3）（all P<0.05）. There was no significant difference in blood oxygen saturation（SpO₂） between the two groups（all P>0.05）. The total incidence of adverse reactions in the observation group was significantly lower than that in the control group（12.00% vs 29.33%, P<0.05）. Conclusion: Dexmedetomidine combined with ropivacaine has a significant effect on brachial plexus block. This combined anesthesia has a shorter onset time, more stable hemodynamics, and lower risk of adverse reactions.更多还原