【摘要】 目的 对去白细胞混合浓缩血小板制备质量及临床应用效果进行调查。方法 将白膜法制备的去白细胞混合浓缩血小板实验组（40例）的质量及临床应用效果与去白细胞单采血小板对照组（40例）的质量及临床应用效果进行对比。结果 经检测实验组和对照组的血小板容量（mL）、血小板计数(×10¹¹)、红细胞混入量（×10⁸）和白细胞残留量（×10⁶）分别为278.90±7.92 vs 276.52±8.01、2.66±0.09 vs 2.66±0.83、0.54±0.42 vs 0.83±0.84、0.29±0.54 vs 0.27±0.51,二者之间表现并无显著差别，且细菌培养结果均为阴性，均符合国家相关标准要求；另在临床应用效果评价指标CCI（×10³,24h）和PPR（%）上分别为15.11±9.86 vs 14.61±12.55和54.23±18.70 vs 61.41±19.09,二者之间表现亦无显著差别，可达到一定程度的治疗效果。结论 去白细胞混合浓缩血小板质量及临床治疗效果与去白细胞单采血小板质量及临床治疗效果一致。更多还原

【Abstract】 Objective To investigate the preparation quality and clinical application effect of pooled platelets with leukocytes reduced. Methods The quality and clinical effect of the buffy-coated method prepared pooled platelets leukocytes reduced（experimental group, n=40） and apheresis platelets leukocytes reduced（control group, n=40） were compared. Results The platelet volume（mL）, platelet count(×10¹¹), red blood cell contamination（×10⁸） and residual white blood cell（×10⁶） of the experimental group and control group were 278.90±7.92 vs 276.52±8.01, 2.66±0.09 vs 2.66±0.83,0.54±0.42 vs 0.83±0.84, 0.29±0.54 vs 0.27±0.51, respectively, with no significant difference. The results of bacterial culture were negative, all met the requirements of relevant national standards. In addition, the CCI（×10³, 24 h） and PPR（%） were 15.11±9.86 vs 14.61±12.55 and 54.23±18.70 vs 61.41±19.09 respectively, with no significant difference, indicating a certain degree of therapeutic effect. Conclusion The quality and clinical therapeutic effect of pooled platelets leukocytes reduced were consistent with that of apheresis platelets leukocytes reduced.更多还原