节点文献
地塞米松植入剂研究进展(综述)
Research progress of dexamethasone implants
【摘要】 植入型给药系统(植入剂)具有生物利用度高,直接作用于靶部位,延长作用时间以提高患者顺应性等特点。地塞米松是一种经典的抗炎、免疫抑制药物,但传统的给药方式会引起一些副作用。因此,开发地塞米松植入剂对提高疗效和用药安全性具有重要意义。该文就地塞米松植入剂在几类疾病治疗中的应用和研究进展进行综述,为开发地塞米松植入剂提供参考。
【Abstract】 Implantable drug delivery systems(implants) are characterized by high bioavailability, direct action on the target site, prolonged action time to improve patient compliance, etc. Dexamethasone is a classic antiinflammatory and immunosuppressive drug, but the traditional way of administration can cause some side effects.Therefore, the development of dexamethasone implants is of great significance to improve the efficacy and drug safety. In this review, the application and research progress of dexamethasone implants in the treatment of several diseases were reviewed, providing reference for the development of dexamethasone implants.
【Key words】 implants; dexamethasone; drug carrier; drug therapy; drug delivery systems;
- 【文献出处】 安徽医专学报 ,Journal of Anhui Medical College , 编辑部邮箱 ,2023年01期
- 【分类号】R943
- 【下载频次】25