【摘要】 [目的]采用响应面法优化SFE-CO₂法萃取金银花精油提取工艺，确定最佳萃取条件。[方法]在单因素试验的基础上，选取对提取率有明显影响的3个因素萃取温度、萃取压力、夹带剂浓度及变化水平，采用Design-Expert 8.05和Box-Benhnken法，以精油得率为评价目标，建立数学回归模型，通过优化获得最佳工艺条件。[结果]金银花精油最佳工艺条件为萃取温度49℃、萃取压力36 MPa、夹带剂浓度73%,精油平均提取率为2.48%。[结论]该试验采用的响应面法方法可靠，具有可操作性，得到的二次回归模型拟合度高，可以为金银花精油工业化生产提供技术支撑，对金银花的进一步开发利用具有一定的指导意义。更多还原

【Abstract】 [Objective] To optimize the SFE-CO₂ extraction process of honeysuckle essential oil by response surface methodology（RSM） and determine the optimal extraction conditions. [Method]On the basis of single factor experiment, the extraction temperature, the extraction pressure, the concentration of entrainer and the change level three factors which have obvious influence on the extraction rate were selected. The method of Design-Expert 8.05 and Box-Benhnken was used to evaluate the yield of essential oil, the mathematical regression model was established, and the optimum technological conditions were obtained by optimization. [Result]The optimum conditions were extraction temperature 49 ℃, extraction pressure 36 MPa and entrainer concentration 73%. The average extraction rate was 2.48%. [Conclusion]The response surface methodology is reliable and operability, and the quadratic regression model obtained is highly fitted, which can provide technical support for the industrial production of honeysuckle essential oil, it has certain guiding significance to the further development and utilization of honeysuckle.更多还原