【摘要】 目的：观察补阳还五汤黄芪不同配比组方对缺血性卒中偏瘫患者康复治疗中的应用价值。方法：将96例缺血性卒中偏瘫患者通过随机数字表法分为低剂量组与高剂量组，每组48例。两组均采用常规基础治疗，其中对照组使用常规剂量黄芪（30g/剂），观察组则给予高剂量（黄芪120g/剂）。治疗3个疗程后，比较两组患者治疗前后的肢体运动功能、生活质量、中医证候评分、血液流变学指标（全血高切粘度、全血低切粘度、血浆粘度）水平及炎症指标。结果：（1）观察组的临床治疗总有效率为95.83%，高于对照组的82.98%（χ~2=8.716）,P<0.05，有统计学意义；（2）观察组治疗后的NIHSS评分低于对照组（t=6.181）,Fugl-Meyer(FMA)评分高于对照组（t=2.918）,P<0.05，有统计学意义；（3）观察组治疗后的BI指数评分高于对照组（t=2.792）,P<0.05，有统计学意义；（4）观察组治疗后的全血高切粘度、全血低切粘度、血浆粘度及炎症指标水平均显著低于对照组，且差异均有统计学意义（P<0.05）。结论：相比于补阳还五汤低剂量黄芪配比，高剂量黄芪配比对缺血性脑卒中患者在缓解神经功能缺损和肢体功能障碍，改善血流变学，降低炎症因子水平等方面有着更为显著的疗效。更多还原

【Abstract】 Objective: To observe the application value of different ratios of astragalus in Buyang Huanwu Decoction to the rehabilitation treatment of patients with ischaemic stroke and hemiplegia. Methods: 96 patients with ischaemic stroke hemiplegia were divided into low-dose group and high-dose group through random number table method, with 48 cases in each group. Both groups used conventional basic treatment, of which the control group used the conventional dose of astragalus(30g/dose), and the observation group gave a high dose(120g/dose of astragalus). After three courses of treatment, the level of limb motor function, quality of life, TCM syndrome score, haemorheology index(whole blood high cut viscosity, whole blood low cut viscosity, plasma viscosity) level and inflammation indicators before and after treatment of the two groups of patients were compared. Results:(1) The total clinical treatment efficiency of the observation group was 95.83%, higher than 82.98% of the control group （χ~2=8.716）, P<0.05, statistically significant;(2) the NIHSS score after treatment of the observation group was lower than that of the control group(t=6.181), Fugl-Meyer(FMA) score is higher than that of the control group(t=2.918), P<0.05, which is statistically significant;(3) The BI index score after treatment in the observation group is higher than that of the control group(t=2.792), P<0.05, which is statistically significant;(4) Total blood hypercision after treatment in the observation group The viscosity, low-cut viscosity of whole blood, plasma viscosity and inflammatory index water are significantly lower than those of the control group on average, and the differences are statistically significant(P<0.05). Conclusion: Compared with the low-dose astragalus ratio of Buyang Huanwu Decoction, the high-dose astragalus ratio has a more significant effect on patients with ischaemic stroke in relieving neurological defects and limb disfunction, improving haemorheology, and reducing the level of inflammatory factors.更多还原