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“清补并用”防治放射性口腔黏膜炎的思路与进展

Progress and Thoughts for Preventing and Treating Radioactive Oral Mucositis Using Clearing Together with Nourishing Method

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【作者】 陈薇伊蒋梅梁嘉琦张晶徐剑焜周小琦林丽珠

【Author】 CHEN Wei-yi;JIANG Mei;LIANG Jia-qi;ZHANG Jing;XU Jian-kun;ZHOU Xiao-qi;LIN Li-zhu;The First Affiliated Hospital of Guangzhou University of Chinese Medicine;The First Clinical Medical School of Guangzhou University of Chinese Medicine;

【通讯作者】 林丽珠;

【机构】 广州中医药大学第一附属医院广州中医药大学第一临床医学院

【摘要】 放疗是头颈部恶性肿瘤的主要治疗手段,放射性口腔黏膜炎是放射线造成的一种口腔黏膜毒性反应,大多数头颈部肿瘤患者在接受放疗的过程中都会经历不同程度的放射性口腔黏膜炎。联合化疗、靶向治疗或免疫治疗的放疗使得该毒性变得更普遍且程度更重,这严重影响了患者的生活质量以及对抗肿瘤治疗的耐受性。中医药已在肿瘤防治的临床实践中广泛应用,能起到增效减毒的作用,因此,研究中医药防治该病的有效方法对于提高患者的抗肿瘤治疗依从性、缩短住院时间、减少抗生素和止痛药的使用以及提高患者生活质量意义重大。

【Abstract】 Radiotherapy is the main treatment for head and neck malignancies. Radiation-induced oral mucositis is a kind of oral mucosal toxicity caused by radiation. The marjority of patients patients with head and neck tumors may undergo different grades of Radiation-induced oral mucositis during the treatments radiotherapy. Radiotherapy combined with chemotherapy,targeted therapy or immunotherapy may increase the incidence rate and the severity of the oral mucisotis,which can seriously affect patients’ life quality and their tolerance to anti-tumor treatments.Traditional Chinese medicine has been widely used preventing and treating cancers,and play a important role in enhancing curative effects and reducing toxicity. Therefore,to further study the traditional Chinese medicine for prevention and treating Radiation-induced oral mucositis is of great significance especially for syndrome differentiation treating, improving patients’ compliance with anti-tumor treatments, shortening hospitalization time,reducing the use of antibiotics and painkillers and improving patients’ quality of life.

【基金】 广州市科技局市校(院)联合资助项目(编号:202201020515);广州中医药大学第一附属医院创新强院二期工程(编号:2019IIT01);广东省高等教育教学改革项目(编号:138)
  • 【文献出处】 中医肿瘤学杂志 ,Journal of Oncology in Chinese Medicine , 编辑部邮箱 ,2022年06期
  • 【分类号】R273
  • 【下载频次】68
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