【摘要】 目的：探索脑梗死患者的中医体质分布规律，研究脑梗死与中医体质的相关性，为中医药防治脑梗死提供循证医学证据。方法：在中国生物医学文献数据库、万方数据、重庆维普、中国知网、Embase和PubMed数据库中检索临床研究脑梗死与中医体质相关性的文献。采用Stata 15.1软件对横断面研究进行单组率的Meta分析，探究脑梗死患者的中医体质分布规律；对病例对照研究进行二分类的Meta分析，探究脑梗死患者中医体质分布与一般人群的差异，并以比值比（OR）或率及其95%置信区间（CI）表达效应值，对发表偏倚应用漏斗图来评价。结果：(1)本研究分析了18个研究，共3 957例样本，发现脑梗死的中医体质分布为痰湿质24%、气虚质19%，可见脑梗死的主要体质类型是痰湿质、气虚质；(2)基于2 646例样本的Meta分析发现，脑梗死患者痰湿质、气虚质、血瘀质体质类型分别是一般人群的4.25、2.78、1.63倍，差异均具有统计学意义。结论：脑梗死的主要体质类型可能是痰湿质、气虚质；脑梗死的高危体质可能是痰湿质、气虚质、血瘀质。更多还原

【Abstract】 Objective: To explore the distribution law of TCM constitution in patients with cerebral infarction, and to study the correlation between TCM constitution and cerebral infarction, so as to provide evidence-based medical evidence for TCM prevention and treatment of cerebral infarction. Methods: Literature on the correlation between cerebral infarction and TCM constitution was searched in China Biomedical Literature Database, Wanfang Data, Chongqing VIP, CNKI, Embase and Pub Med databases. Stata 15.1 software was used to conduct a meta-analysis of the single group rate in the cross-sectional study to explore the distribution law of TCM constitution of patients with cerebral infarction. A binary meta-analysis of case-control studies was conducted to explore the differences between TCM constitution distribution of cerebral infarction patients and the general population, and funnel plot was used to evaluate publication bias by odds ratio or rate and 95% confidence interval expression effect values. Results:(1) This study analyzed 18 studies, a total of 3 957 cases, and found that the distribution of TCM constitution of cerebral infarction was phlegm-dampness of 24% and Qi(气) deficiency of 19%, indicating that the main constitution types of cerebral infarction were phlegm-dampness and Qi deficiency.(2) Based on the meta-analysis of 2 646 cases, it was found that the constitution types of phlegm-dampness, Qi deficiency and bloodstasis in cerebral infarction patients were 4.25, 2.78 and 1.63 times that of the general population, respectively, and the differences were statistically significant. Conclusion: Phlegm-dampness constitution and Qi deficiency constitution are the main constitutional types of cerebral infarction; phlegm-dampness constitution, Qi deficiency constitution and blood stasis constitution are high-risk conditions for developing cerebral infarction.更多还原