【摘要】 IgA血管炎过去称为过敏性紫癜，是一种白细胞碎裂性血管炎，其发病机制不明。大量研究发现链球菌感染及免疫紊乱可能是导致其发生的原因。文章主要探究可能引起IgA血管炎的链球菌生物膜的结构，如AgⅠ/Ⅱ家族蛋白、脱氧核糖核酸酶、脂壁磷酸酶、胶原样蛋白-1、半胱氨酸蛋白酶等，以及免疫紊乱中的Th1/Th2比例失衡。更多还原

【Abstract】 IgA vasculitis used to be called allergic purpura, which is a kind of leucocyte fragmentation vasculitis with unknown pathogenesis. A large number of studies have found that streptococcal infection and immune disorders may be the cause of the disease. This article mainly focuses on the structure of streptococcal biofilms that may cause IgA vasculitis, such as AgⅠ/Ⅱ family proteins, deoxyribonuclease, lipid wall phosphatase, collagen-like protein-1, cysteine protease, etc., and Th1/Th2 ratio imbalance in immune disorders.更多还原