【摘要】 目的：研究心脉隆注射液对心脏瓣膜术后患者左心室射血分数的影响。方法：以2020年1月-2022年1月在赣州市人民医院就诊并接受心脏瓣膜术的70例患者为研究对象，采用随机数字表法分为对照组35例和观察组35例。对照组术后给予米力农注射液治疗，观察组术后给予心脉隆注射液治疗。比较两组患者的左心室舒张末容积（LVEDV）、左心室收缩末期容量（LVESV），并计算左心室射血分数（LVEF）、氨基末端脑利钠肽前体（NT-proBNP）、肌钙蛋白T(cTnT)。结果：手术结束时，两组患者的LVEDV、LVESV、LVEF比较，差异均无统计学意义（P>0.05）；术后5 d，两组患者的LVESV与手术结束时比均有所降低，LVEDV、LVEF均高于手术结束时（P<0.05），观察组患者的LVEDV、LVESV、LVEF改善情况均优于对照组（P<0.05）。手术结束时，两组患者血清中的NT-proBNP、cTnT比较，差异均无统计学意义（P>0.05）；术后72 h时，两组患者NT-proBNP和cTnT水平均低于手术结束时，且观察组均低于对照组，差异均有统计学意义（P<0.05）。观察组并发症发生率低于对照组，差异有统计学意义（P<0.05）。结论：对心脏瓣膜手术患者给予心脉隆注射液进行术后治疗，对提高患者心脏功能、降低并发症发生率效果显著。更多还原

【Abstract】 Objective: To study the effect of Xinmailong Injection on left ventricular ejection fraction in patients after heart valve surgery. Method: A total of 70 patients who received heart valvular surgery in Ganzhou People’s Hospital from January 2020 to January 2022 were selected as the research objects. They were divided into control group(35 cases) and observation group(35 cases) by random number table method. The control group was given postoperative treatment with Milrinone Injection, and the observation group was given postoperative treatment with Xinmailong Injection. Left ventricular end-diastolic volume(LVEDV) and left ventricular end-systolic volume(LVESV) were compared between the two groups, and left ventricular ejection fraction(LVEF), NT-proBNP and cTnT were calculated. Result: At the end of operation, there were no significant differences in LVEDV, LVESV and LVEF between two groups(P>0.05); 5 days after surgery, LVESV of the two groups were decreased compared with the end of surgery, LVEDV and LVEF were higher than those of the end of surgery(P<0.05), the improvement of LVEDV, LVESV and LVEF of the observation group were better than those of the control group(P<0.05). At the end of operation, there were no significant differences in serum levels of NT-proBNP and cTnT between the two groups(P>0.05); 72 h after surgery, the levels of NT-proBNP and cTnT in the two groups were lower than those of the end of surgery, and the observation group were lower than those of the control group, the differences were statistically significant(P<0.05). The incidence of complications in observation group was lower than that in control group, the difference was statistically significant(P<0.05). Conclusion: Xinmailong Injection can significantly improve the cardiac function and reduce the incidence of complications in patients undergoing heart valve surgery.更多还原