【摘要】 目的 分析邯郸地区妊娠期糖尿病孕妇晚期下生殖道感染现状及对新生儿败血症感染的影响。方法 选取3400例邯郸地区2012年1月-2020年3月妊娠期糖尿病孕妇晚期为观察组，另选取3000例同地区、同期正常妊娠晚期孕妇为对照组。统计观察组下生殖道感染发生率、两组新生儿败血症发生率，分析妊娠期糖尿病孕妇晚期下生殖道感染的危险因素和下生殖道感染对新生儿败血症的感染的影响。结果 3400例妊娠期糖尿病孕妇晚期患者中有1500例发生下生殖道感染，发生率为44.12%。单因素分析所示，妊娠期糖尿病孕妇晚期发生下生殖道感染与年龄、分娩史、流产史、HbA1c、既往生殖道感染史、混用外阴清洗工具卫生用具、空腹血糖、文化程度有关，具有统计学差异（P<0.05）。Logistics回归分析结果显示，上述因素均为影响妊娠期糖尿病孕妇晚期发生下生殖道感染的主要危险因素（P<0.05）。观察组中下生殖道感染产妇、下生殖道未感染产妇新生儿败血症发生率高于对照组，观察组中下生殖道感染产妇的新生儿败血症发生率高于下生殖道未感染产妇，具有统计学差异（P<0.05）。结论 妊娠期糖尿病孕妇晚期下生殖道感染与多种因素相关，下生殖道感染会增加新生儿败血症感染的发生率，可对具体因素采用相应措施，以此降低下生殖道感染在糖尿病妊娠末期的发生率，减少下生殖道感染对产妇及新生儿的影响。更多还原

【Abstract】 Objective Analyze the current status of late-stage lower reproductive tract infection in pregnant women with gestational diabetes in Handan area and the impact on neonatal septicemia infection.Methods 3400pregnant women with late gestational diabetes from January 2012to March 2020in Handan area were selected as the observation group,and 3000pregnant women with normal third trimester in the same region and the same period were selected as the control group.The incidence of lower genital tract infection and incidence of neonatal sepsis in two groups were analyzed.Hair coloring risk factors in late stage of GDM and risk of neonatal sepsis were analyzed.Results Among the3400late-stage pregnant women with gestational diabetes mellitus,1500had lower genital tract infections,the incidence was 44.12%.Univariate analysis showed that late reproductive tract infections in gestational diabetes mellitus were associated with age,history of childbirth,history of abortion,HbA1c,history of reproductive tract infection,mixed use of genital cleaning tools,fasting blood glucose and education level(P<0.05).Logistics regression analysis showed that all the above factors were the main risk factors for late reproductive tract infections in pregnant women with gestational diabetes mellitus(P<0.05).The incidence of neonatal sepsis in the observation group was higher than that in the control group.The incidence of neonatal sepsis in the observation group was higher than that in the control group(P<0.05).Conclusion Late lower reproductive tract infections in pregnant women with gestational diabetes are related to many factors.Lower reproductive tract infections will increase the incidence of neonatal septicemia infection.Corresponding measures can be taken for specific factors to reduce the occurrence of lower reproductive tract infections in the end of diabetic pregnancy.Rate,reduce the impact of lower reproductive tract infections on women and newborns.更多还原