【摘要】 目的 调查分析广东省典型氟化工区周边种植的蔬菜中3种全氟化合物及2种氯代多氟醚基磺酸的污染现状及膳食暴露风险。方法 2019年在广东省3个氟化工区周边随机采集种植蔬菜及非氟化工区农贸市场市售样品共96份，采用同位素稀释超高效液相色谱-三重四级杆质谱法检测样品中全氟辛烷磺酸（PFOS）、全氟辛酸（PFOA）、全氟己烷磺酸（PFHxS）、6:2氯代多氟醚基磺酸（6:2 Cl-PFESA）和8:2氯代多氟醚基磺酸（8:2 ClPFESA）的浓度，并采用点评估法对食用蔬菜暴露5种化合物的健康风险进行评估。结果 所有样品均检出PFOS和PFOA，仅在2份叶类蔬菜检出氯代多氟醚基磺酸。样品中5种化合物的平均浓度之和（∑₃PFASs+∑₂ClPFESA）为0.792 ng/g fw（fresh weight，鲜质量），其中氟化工区周边样品的平均浓度为农贸市场市售样品的2倍。在3类蔬菜样品中，叶类蔬菜5种化合物的平均浓度之和最高，为1.11 ng/g fw。暴露评估结果显示，通过食用氟化工区周边种植的蔬菜暴露PFOS、PFOA和PFHxS的范围为0.185～2.35 ng/kg·BW，其中PFOS和PFOA的危害指数（HI）大于1,2种氯代多氟醚基磺酸的暴露水平较低。结论 居民食用氟化工区周边种植的叶类和瓜果类蔬菜暴露PFOS和PFOA的水平已超过健康指导值，存在潜在健康风险。经蔬菜暴露2种氯代多氟醚基磺酸的健康风险较低，但仍需关注。更多还原

【Abstract】 Objective To investigate the contamination status and dietary exposure risk of 3 perfluorinated substances and 2 chlorine substituted perfluoroalkyl ether sulfonate acids in fresh vegetables planted in the vicinity of typical fluorine chemical industry parks located in Guangdong province.MethodsNinety six vegetables were collected from the vicinity of 3 typical fluorine chemical industry parks and local markets in 2019.The concentrations of 3 perfluorinated substances[perfluorooctane sulfonate acid(PFOS),perfluorooctanoic acid(PFOA),perfluorohexanesulfonic acid(PFHxS)]and 2chlorine substituted perfluoroalkyl ether sulfonate acids(6:2 Cl-PFESA and 8:2 Cl-PFESA)in fresh vegetables were detected using isotope dilution method by UPLC-QqQ-MS,and the point estimate was employed to estimate the levels of dietary exposure from fresh vegetables.ResultsPFOS and PFOA were detected in all samples,while chlorine substituted perfluoroalkyl ether sulfonates were detected in 2 leafy vegetable samples.The sum of average concentration of PFASs and Cl-PFESAs in vegetable samples was 0.792 ng/g fw(fresh weight,fw),and it was two-fold higher compared the samples around the fluorine chemical industrial with the samples from local markets.The average concentration of 5 chemicals(1.11 ng/g fw)was the highest in leafy vegetables.The results of dietary exposure assessment indicated that the exposure levels of 3 perfluorinated compounds by consumption of fresh vegetables which planted surrounding fluorine chemical industry parks were 0.185-2.35 ng/kg·BW.The hazard indexes(HI) of PFOS and PFOA were greater than 1.The exposure level of chlorine substituted perfluoroalkyl ether sulfonate acids were lower.ConclusionThe exposures of PFOS and PFOA of local general population exceeded the established thresholds for the adult residents.The risks of 2 chlorine substituted perfluoroalkyl ether sulfonate acids exposure from vegetables were low,which still need to be concerned.更多还原