【摘要】 目的：观察认知行为疗法联合超低频经颅磁刺激治疗抑郁症患者的效果。方法：选取120例抑郁症患者为研究对象，按照随机数字表法分为观察组与对照组各60例。对照组采用超低频经颅磁刺激治疗，观察组在对照组基础上联合认知行为疗法治疗，比较两组临床疗效、汉密尔顿抑郁量表（HAMD）评分、杨氏狂躁评定量表（YMRS）评分、一般自我效能感量表（GSES）评分和韦氏记忆量表评分。结果：观察组治疗总有效率为95.00%，明显高于对照组的75.00%，差异有统计学意义（P<0.05）；治疗后，两组HAMD、YMRS评分均低于治疗前，且观察组低于对照组，两组GSES评分均高于治疗前，且观察组高于对照组，差异有统计学意义（P<0.05）；治疗后，两组韦氏记忆量表中再认、图片、联想及背数等维度评分均低于治疗前，且观察组低于对照组，差异有统计学意义（P<0.05）。结论：认知行为疗法联合超低频经颅磁刺激治疗抑郁症患者可提高治疗总有效率和GSES评分，降低HAMD、YMRS评分，以及改善记忆功能，效果优于单纯超低频经颅磁刺激。更多还原

【Abstract】 Objective: To observe effects of cognitive behavior therapy combined with ultra-low frequency transcranial magnetic stimulation on patients with depression. Methods: 120 patients with depression were selected as the research objects and were divided into observation group and control group according to the random number table method, 60 cases in each. The control group was treated with ultra-low frequency transcranial magnetic stimulation, while the observation group was treated with cognitive behavior therapy on the basis of that of the control group. The efficacy, the Hamilton depression rating scale(HAMD) score, the Young’s mania rating scale(YMRS) score, the general self-efficacy scale(GSES) score and the Wechsler memory scale score were compared between the two groups. Results: The total effective rate of the observation group was 95.00%, which was significantly higher than the control group of 75.00%, and the difference was statistically significant(P<0.05). After the treatment, the HAMD and YMRS scores of the two groups were lower than those before the treatment, and those of the observation group was lower than those of the control group; the GSES scores of the two groups were higher than those before treatment, and that of the observation group was higher than that of the control group; and the differences were statistically significant(P<0.05). Further, after the treatment, the recognition, pictures,memorizing numbers and other dimensions scores of Wechsler memory scale in the two groups were lower than those before the treatment, those of the observation group were lower than those of the control group, and the differences were statistically significant(P<0.05). Conclusions: Cognitive behavior therapy combined with ultra-low frequency transcranial magnetic stimulation in the treatment of the depression patients can improve the total effective rate and the GSES score, reduce the HAMD score and the YMRS score, and improve the memory function. Moreover, it is superior to single ultra-low frequency transcranial magnetic stimulation.更多还原