【摘要】 目的 探讨六字诀呼吸操联合穴位按摩对慢性阻塞性肺疾病（COPD）稳定期患者肺功能、呼吸困难症状、生活质量的影响。方法 纳入2017年4月至2019年4月在杭州市中医院老年病科、呼吸科及社区门诊接受治疗的中重度COPD稳定期患者160例，采用随机数字表法将患者分为常规治疗组和呼吸康复组，每组80例。常规治疗组给予抗炎、氧疗、止咳化痰、长效支气管扩张药物等常规治疗，呼吸康复组在常规治疗基础上辅以六字诀呼吸操联合穴位按摩康复治疗。比较两组患者治疗前、治疗后3、6、12个月肺功能指标[第1秒用力呼气容积（FEV₁）、用力肺活量（FVC）、FEV₁/FVC]、呼吸困难程度[采用COPD评估测试（CAT）评分评估]、活动能力[采用6 min步行试验（6MWT）评估]及生活质量[采用圣乔治医院呼吸问题调查问卷（SGRQ）评估]变化情况。结果 治疗后3、6、12个月呼吸康复组FEV₁、FVC、FEV₁/FVC均高于常规治疗组，CAT评分及SGRQ评分均低于常规治疗组，6MWT均高于常规治疗组，差异均有统计学意义（均P<0.05）。结论 六字诀呼吸操联合穴位按摩能够有效改善中重度COPD稳定期患者肺功能、生活质量和呼吸困难症状。更多还原

【Abstract】 Objective To explore the efficacy of Liuzijue breathing exercise combined with acupoint massage in improving pulmonary function, dyspnea symptoms and quality of life in patients with stable chronic obstructive pulmonary disease（ COPD）. Methods A total of 160 patients with moderate to severe COPD in stable stage who were treated in Hangzhou Hospital of Traditional Chinese Medicine from April 2017 to April 2019 were enrolled. The patients were randomly assigned into two groups with 80 cases in each group, patients in control group received conventional treatments including oxygen therapy, and anti-inflammatory, antitussive phlegm-relieving, long-acting bronchodilator drugs. Patients in respiratory rehabilitation group received additional Liuzijue breathing exercise and acupoint massage on the basis of conventional treatment. The pulmonary function tests were performed, dyspnea severity was assessed with COPD assessment test（CAT）,the mobility was assessed with 6 minute walking test（6MWT） and the quality of life was assessed with St George’s Hospital respiratory questionnaire（SGRQ） before treatment, 3, 6 and 12 months after treatment in two groups. Results At 3, 6, and12 months after treatment, the pulmonary function parameters FEV₁, FVC and FEV₁/FVC in respiratory rehabilitation group were higher than those in control group, CAT score and SGRQ score in respiratory rehabilitation group were lower than those in control group, and 6MWT were higher than those in control group（all P<0.05）. Conclusion The Liuzijue breathing exercise combined with acupoint massage can effectively improve lung function, quality of life and dyspnea symptoms in patients with moderate to severe stable COPD.更多还原