【摘要】 目的分析不同体重组人群[小体重组（<45 kg）、标准体重组（45～60 kg）、大体重组（>60 kg）]的骨矿含量结果,探索体重对骨矿含量及其标化的影响。方法纳入290例50～80岁绝经后女性,按体重大小分为大体重组、标准体重组、小体重组。通对不同体重组人群的腰椎L_1～4、股骨的骨矿含量及骨密度进行测量,并对测量结果进行比较分析。同时将年龄、体重作为应变量,腰椎或股骨颈骨矿含量作为自变量,进行多重线性回归分析。结果低体重组的腰椎或股骨颈骨密度T值、骨矿含量均明显低于标准体重组和高体重组人群。随着年龄增长,L_1～4及股骨颈骨矿含量均下降,年龄每升高1岁,L_1～4骨矿含量下降0.364 g、股骨颈骨矿含量下降0.031 g;随着体重增长,L_1～4及股骨颈骨矿含量均升高,体重每增长1 kg, L_1～4骨矿含量升高0.548 g、股骨颈骨矿含量升高0.025 g。结论成年女性的体重与骨矿含量显著正相关,因此,体重是骨矿含量标化的重要指标之一,可以避免骨质疏松的漏误诊。更多还原

【Abstract】 Objective To analyze the bone mineral content(BMC) result in underweight group(<45 kg), standard weight group(45-60 kg), and overweight group(>60 kg), and to explore the influence of body weight on BMC and its standardization. Methods A total of 290 postmenopausal women aged from 50 to 80 years old were enrolled in this study. They were divided into the underweight group(<45 kg), standard weight group(45-60 kg), and overweight group >60 kg), respectively. BMC and BMD of the lumbar vertebrae 1-4 and femur were measured with DXA and analyzed in different weight groups. Multiple linear regression analysis was performed to explore the influence of age and weight in BMC. Results T value and BMC of the lumbar spine or femoral neck in underweight group were lower than those in standard weight group and overweight group. With the increase of age, BMC of the lumbar vertebrae and femoral neck decreased. With 1-year increase in age, BMC of the lumbar vertebrae and the femoral neck decreased by 0.364 g and 0.031 g, respectively. With the increase of body weight, BMC of the lumbar vertebrae and femoral neck increased. With 1 kg increase in weight, BMC of the lumbar vertebrae and the femoral neck increased by 0.548 g and 0.025 g, respectively. Conclusion There is a significant positive correlation between body weight and BMC in adult women. Therefore, body weight is one of the important indicators in BMC standardization, which can avoid missing diagnosis or misdiagnosis of osteoporosis.更多还原