【摘要】 目的 探讨开腹肝肿瘤切除术与腹腔镜肝肿瘤切除术治疗肝肿瘤的临床效果及对肝功能、炎症指标的影响。方法 选取2017年3月至2021年8月贵州省黔东南州人民医院收治的60例肝肿瘤患者作为研究对象，采用随机数字表法将其分为对照组与试验组，每组各30例。对照组患者采用开腹肝肿瘤切除术治疗，试验组患者采用腹腔镜肝肿瘤切除术治疗。比较两组患者的临床指标、肝功能、炎症指标及并发症发生情况。结果 试验组患者的术中出血量少于对照组，术后并发症总发生率低于对照组，差异有统计学意义（P<0.05）。试验组患者的胃肠道恢复时间、引流管拔管时间、住院时间短于对照组，差异有统计学意义（P<0.05）。试验组患者术后的谷草转氨酶、谷丙转氨酶、总胆红素、C-反应蛋白（CRP）水平低于对照组，差异有统计学意义（P<0.05）。结论 腹腔镜下肝肿瘤切除术具有显著的临床效果，能显著改善肝功能，减轻炎症反应，是一种微创、有效和安全的手术。更多还原

【Abstract】 Objective To explore the clinical efficacy of open liver tumor resection and laparoscopic liver tumor resection in treatment of liver tumors and their effect on liver function and inflammatory indexes. Methods A total of 60patients with liver tumors treated in Qiandongnan Prefecture People′s Hospital, Guizhou Province from March 2017 to August 2021 were selected as the research objects and divided into control group and experimental group by random number table method, with 30 cases in each group. The patients in the control group were treated with open liver tumor resection, and the patients in the experimental group were treated with laparoscopic liver tumor resection. The clinical indexes, liver function, inflammatory indexes and incidence of complications of the two groups were compared. Results The amount of intraoperative bleeding in the experimental group was less than that in the control group, and incidence of postoperative complications in the experimental group was lower than that in the control group, and the differences were statistically significant(P<0.05). The recovery time of gastrointestinal tract, extubation time of drainage tube and hospital stay in the experimental group were shorter than those in the control group, and the differences were statistically significant(P<0.05). The levels of aspartate aminotransferase, alanine aminotransferase, total bilirubin and C-reactive protein(CRP) in the experimental group were lower than those in the control group, and the differences were statistically significant(P<0.05). Conclusion Laparoscopic liver tumor resection has significant clinical efficacy, can significantly improve liver function and significantly reduce inflammatory reaction. It is a minimally invasive, effective and safe operation.更多还原