【摘要】 目的 通过比较下肢动脉硬化闭塞症（ASO）经皮血管腔内成形术（PTA）前后的经皮氧分压（TcPO₂）、踝肱指数（ABI）、趾肱指数（TBI）的变化，评价TcPO₂在评估下肢ASO患者PTA疗效的临床价值。方法 ASO患者101例，下肢ASO患肢111例，行PTA术后2～9 d复查TcPO₂、ABI及TBI。根据有无T2DM分为T2DM组（n=57）及单纯ASO组（ASO,n=44）。根据术前TcPO₂水平分为重度缺血组（n=38）、轻度度缺血组（n=37）及正常组（Con,n=36）。根据手术方式分为球囊扩张术组（n=56）、球囊扩张+支架植入术组（n=37）及支架植入术组（n=18）。比较3种检测方法的检测结果。结果 重度及轻度缺血组术后TcPO₂、ABI、TBI高于术前（P<0.05）。球囊扩张术及支架术组术后TcPO₂、ABI、TBI高于术前（P<0.05），球囊扩张+支架植入术组术后ABI、TBI高于术前（P<0.05）。结论 TcPO₂可作为评估下肢ASO行PTA疗效的临床指标之一。TcPO₂在评价微循环状态方面优于ABI、TBI。更多还原

【Abstract】 Objective To identify the clinical value of percutaneous oxygen partial pressure （TcPO₂） in evaluating the efficacy of percutaneous transluminal angioplasty （PTA）in lower extremity arteriosclerosis obliterans（ASO）patients by comparing the changes of TcPO₂,ankle brachial index （ABI） and toe brachial index （TBI） before and after PTA.Methods TcPO₂,ABI and TBI of 111 patients with ASO were examined 2～9 days after PTA. According to the presence of type 2 diabetes mellitus（T2 DM）,they were divided into T2 DM group （n=57） and ASO group（n=44）. According to the level of TcPO₂ before surgery,they were divided into severe ischemia group（n=38）,mild ischemia group （n=37） and normal group（n=36）. According to the surgical methods,they were divided into balloon dilation group（n=56）,balloon dilation + stent implantation group （n=37） and stent implantation group （n=18）.Results The postoperative TcPO₂（mmHg）,ABI and TBI in severe and mild ischemic groups were higher than before operation（P<0. 05）. TcPO₂,ABI and TBI in balloon dilation and stenting group increased after operation （P< 0. 05）. The postoperative ABI and TBI were higher in the balloon dilation+stent implantation group than before operation （P<0. 05）.Conclusion TcPO₂ can be used as one of the clinical indicators to evaluate the efficacy of PTA in lower extremity ASO. TcPO₂ is superior to ABI and TBI in evaluating microcirculation status.更多还原