【作者】
王文雅；
林江涛；
刘春涛；
唐华平；
霍建民；
顾玉海；
刘荣玉；
陈萍；
袁雅冬；
杨晓红；
许建英；
孙德俊；
李娜嘉；
姜淑娟；
陈一强；
王长征；
杨岚；
刘晓菊；
杨冬；
张伟；
陈卓昌；
林其昌；
周建英；
周新；
胡成平；
蒋萍；
周玮；
张捷；
蔡绍曦；
邱晨；
黄茂；
黄奕江；
刘辉国；
【Author】
WANG Wenya;LIN Jiangtao;LIU Chuntao;TANG Huaping;HUO Jianmin;GU Yuhai;LIU Rongyu;CHEN Ping;YUAN Yadong;YANG Xiaohong;XU Jianying;SUN Dejun;LI Najia;JIANG Shujuan;CHEN Yiqiang;WANG Changzheng;YANG Lan;LIU Xiaoju;YANG Dong;ZHANG Wei;CHEN Zhuochang;LIN Qichang;ZHOU Jianying;ZHOU Xin;HU Chengping;JIANG Ping;ZHOU Wei;ZHANG Jie;CAI Shaoxi;QIU Chen;HUANG Mao;HUANG Yijiang;LIU Huiguo;Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, National Clinical Research Center of Respiratory Disease;Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University;Department of Pulmonary and Critical Care Medicine, Qingdao Municipal Hospital;Department of Respiratory Medicine, The First Affiliated Hospital of Harbin Medical University;Department of Respiratory Medicine, Qinghai Provincial People’s Hospital;Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University;Department of Respiratory Medicine, General Hospital of Northern Theater Command;Department of Respiratory Medicine, The Second Hospital of Hebei Medical University;Department of Pulmonary and Critical Care Medicine, Xinjiang Uiger Municipal People’s Hospital;Department of Pulmonary and Critical Care Medicine, Shanxi Bethune Hospital;Department of Pulmonary and Critical Care Medicine, Inner Mongolia Autonomous Region People’s Hospital;Department of Respiratory Medicine, Daqing Oilfield General Hospital;Department of Pulmonary and Critical Care Medicine, Shandong Provincial Hospital;Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University;Department of Respiratory Medicine, Xinqiao Hospital of Army Medical University;Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital of Xi’an Jiaotong University;Department of Geriatric Respiration, The First Hospital of Lanzhou University;Department of Respiration, Zhongshan Hospital, Fudan University;Department of Respiratory Medicine, The First Affiliated Hospital of Nanchang University;Department of Respiratory Medicine, Henan Provincial People’s Hospital;Department of Respiratory Medicine, The First Affiliated Hospital of Fujian Medical University;Department of Respiratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, The First Hospital of Zhejiang Province;Department of Respiratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University;Department of Pulmonary and Critical Care Medicine, Xiangya Hospital of Central South University;Department of Respiratory Medicine, Tianjin First Central Hospital;Department of Pulmonary and Critical Care Medicine, General Hospital of Ningxia Medical University;Department of Pulmonary and Critical Care Medicine, The Second Hospital of Jilin University;Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern University of Science and Technology;Department of Pulmonary and Critical Care Medicine, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University;Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University;Department of Pulmonary and Critical Care Medicine, Hainan General Hospital;Department of Respiratory Medicine, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology;the China Asthma Research Collaboration Network;
【通讯作者】
林江涛;
【机构】
中日友好医院呼吸与危重症医学科国家呼吸疾病临床研究中心；
四川大学华西医院呼吸与危重症医学科；
青岛市立医院呼吸与危重症医学科；
哈尔滨医科大学第一附属医院呼吸科；
青海省人民医院呼吸科；
安徽医科大学第一附属医院呼吸与危重症医学科；
北部战区总医院呼吸科；
河北医科大学第二附属医院呼吸科；
新疆维吾尔自治区人民医院呼吸与危重症医学科；
山西白求恩医院呼吸与危重症医学科；
内蒙古人民医院呼吸与危重症医学科；
大庆油田总医院呼吸科；
山东省人民医院呼吸与危重症医学科；
广西医科大学第一附属医院呼吸内科；
陆军医科大学新桥医院呼吸内科；
西安交通大学附属第一医院呼吸与危重症医学科；
兰州大学第一医院老年呼吸科；
复旦大学附属中山医院呼吸内科；
南昌大学第一附属医院呼吸内科；
河南省人民医院呼吸内科；
福建医科大学第一附属医院呼吸内科；
浙江大学医学院附属第一医院呼吸内科；
上海交通大学医学院附属上海市第一人民医院呼吸内科；
中南大学湘雅医院呼吸与危重症医学科；
天津市第一中心医院呼吸内科；
宁夏医科大学总医院呼吸与危重症医学科；
吉林大学第二医院呼吸与危重症医学科；
南方科技大学附属南方医院呼吸与危重症医学科；
暨南大学第二临床医学院深圳市人民医院呼吸与危重症医学科；
南京医科大学附属第一医院呼吸与危重症医学科；
海南省人民医院呼吸与危重症医学科；
华中科技大学同济医学院附属同济医院呼吸内科；
中国哮喘研究协作组；
【摘要】 目的 分析未控制的哮喘患者药物治疗依从性与肺功能、气道炎症水平、哮喘控制水平以及患者生活质量之间的关系,为改善患者依从性和提高哮喘控制水平提供依据。方法 以我国大陆28个省市32家三甲医院未达到哮喘控制且依从性差的哮喘患者作为研究对象,通过问卷调查的方式收集患者一般资料,所有患者均行肺功能、气道炎症水平检测,分析我国成人哮喘患者治疗依从性。结果 调查共计923例患者,调查问卷回收率100%。哮喘疾病认知相关问题回答完全正确者占243例(26.33%),哮喘疾病认知相关问题不能完全回答正确者占680例(73.67%)。哮喘患者治疗依从性与肺功能指标呈正相关,与呼出气一氧化氮呈明显负相关。治疗依从性高的哮喘患者,其哮喘控制水平和生活质量更高。哮喘患者治疗依从性不佳将会导致肺功能下降和气道炎症水平升高,使哮喘控制水平以及生活质量下降。结论 哮喘治疗依从性与肺功能及气道炎症水平、哮喘控制水平和生活质量相关。更多还原
【Abstract】 Objective To analyze the relationship between medication compliance of patients with uncontrolled asthma and lung function,airway inflammation level, asthma control level and quality of life so as to obtain important references for improving patient compliance and asthma control level in the future. Methods Questionnaires were performed in asthma patients who did not achieve asthma control and had poor compliance in 32 third-class hospitals in 28 provinces of China mainland. All patients were tested for lung function and airway inflammation levels. So the relevant data of asthma compliance was investigated and analyzed. Results A total of 923 patients were investigated and the questionnaire recovery rate was 100%. Two hundred and forty-three(26.33%) answered cognitive related questions about asthma completely correctly. Treatment compliance in asthma patients was positively correlated with lung function and significantly negatively correlated with exhaled nitric oxide. Better treatment compliance in asthma has higher level of asthma control and quality of life. Poor compliance in asthma patients will lead to decreased lung function and elevated levels of airway inflammation, resulting in decreased asthma control and quality of life. Conclusion Asthma treatment compliance is related to lung function, airway inflammation, asthma control level and quality of life.更多还原
【基金】 首都医学发展科研基金(2015-BKJ-001)
