【摘要】 传统疫苗在传染病防治领域发挥了重要作用，但其仍不同程度地存在安全性差、免疫原性低、稳定性差、难以诱导持久免疫反应等问题。纳米递送系统可提高抗原稳定性并靶向抗原提呈细胞，促进抗原提呈细胞成熟并激活特异性免疫反应。目前已有大量研究利用纳米递送载体制备高效疫苗。该文简要阐述纳米递送载体在增强疫苗免疫效应中的应用。更多还原

【Abstract】 Traditional vaccines have played an important role in preventing and treating infectious diseases.However, many problems, such as dissatisfied safety, low immunogenicity, poor stability, and limited durable immune responses, restricted further applications of traditional vaccines.Nano-delivery systems can improve antigen stability, target antigen-presenting cells, promote the maturation of antigen-presenting cells, and activate specific immune responses.Presently, a large number of studies developed efficient vaccines using nano-delivery systems.This review briefly summarized the application of nano-delivery systems to enhance the immune effects of vaccines.更多还原