节点文献
韦企平教授治疗视神经萎缩的用药规律及特点分析
Analysis of Professor Wei Qiping’s medication rules and characteristics in treating optic atrophy
【摘要】 目的 基于数据挖掘整理并总结韦企平教授治疗视神经萎缩用药规律及特点。方法 收集2015年1月至2022年4月韦企平教授临床用于治疗视神经萎缩的中药处方,分析治疗视神经萎缩中药的频次、功效、四气、五味及归经,用关联规则和聚类分析和因子分析挖掘潜在用药规律。结果 共纳入692首处方,212味中药。最常用的中药有当归、枳壳、枸杞子;补虚药、解表药、理气药位居用药种类前3位;药性多为平;药味以甘、苦、辛居多;归经多归肝、脾;聚类分析获得8组核心药物组合;因子分析共提取6个公因子。结论 韦企平教授治疗视神经萎缩重视疏肝解郁,同时兼顾化痰活血、养血健脾。
【Abstract】 Objective To organize and summarize the rules and characteristics of Professor Wei Qiping’s medication for optic atrophy based on data mining. Methods From January 2015 to April 2022, the prescriptions of traditional Chinese medicine used by Professor Wei Qiping for the treatment of optic atrophy were collected. The frequency, efficacy, four nature, five flavours, and channel tropism of traditional Chinese medicine for optic atrophy were analyzed. Association rules, cluster analysis, and factor analysis were used to explore potential medication rules. Results A total of 692 prescriptions and 212 traditional Chinese medicine were included. The most commonly used traditional Chinese medicines were Angelicae Sinensis Radix, Aurantii Fructus, Lycii Fructus; reinforcing-deficiency drugs, superficies-relieving drugs, and regulating qi-flowing drugs ranked the top three in the category of drugs. Drug properties were mostly plain; the taste of drug was mostly sweet, bitter, and pungent; the channel tropism were mainly liver and spleen channels. Eight core drug combinations were obtained by cluster analysis. A total of six common factors were extracted by factor analysis. Conclusion In the treatment of optic atrophy, Professor Wei Qiping attaches great importance to dispersing stagnated liver qi for relieving qi stagnation, while taking into account resolving phlegm and promoting blood circulation, nourishing blood and strengthening spleen.
【Key words】 Optic atrophy; Medication rules; Data mining; Traditional Chinese medicine; Wei Qiping;
- 【文献出处】 中国医药导报 ,China Medical Herald , 编辑部邮箱 ,2022年29期
- 【分类号】R276.7;R249
- 【下载频次】52