【摘要】 目的 分析冯建华教授治疗2型糖尿病的用药规律和特点,为中医药治疗糖尿病提供参考。方法 选取北京中医药大学与中国科学院计算技术研究所共同开发的名医传承系统数据库中收集到的山东中医药大学第二附属医院2000年1月到2020年12月冯建华教授治疗2型糖尿病患者的门诊中药处方数据,通过数据分析统计药物使用频次、药味、归经频次,通过关联分析发现常用药对,通过构建药物关系网络图提取核心处方。结果 本研究共纳入120例2型糖尿病患者的处方,共使用中药96味。药物频次出现的前5味依次是生地黄、黄连、知母、玉米须、丹参;药味使用频率前5位依次为甘、苦、辛、酸、淡味;归经频率前5位依次为肝、肺、肾、胃、脾经;归纳最常用药对为生石膏-知母。核心处方为生地黄、丹参、玉米须、黄连、知母、五味子、生石膏、葛根。结论 冯教授治疗糖尿病擅用养阴清热药物,药味以甘味、苦味居多,石膏-知母最常搭配使用。更多还原

【Abstract】 Objective To analyze the drug rule and characteristics of Professor Feng Jianhua in the treatment of diabetes mellitus type 2, and to provide reference for the treatment of diabetes mellitus with traditional Chinese medicine. Methods The outpatient traditional Chinese medicine prescription data of Professor Feng Jianhua in the Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine for the treatment of diabetes mellitus type 2 patients from January 2000 to December 2020 were collected from the database of Famous Doctor Inheritance System jointly developed by Beijing University of Chinese Medicine and Institute of Computing Technology,Chinese Academy of Sciences. Through data analysis, drug use frequency, drug taste and channel frequency were counted,common drug pairs were found through association analysis, and core prescriptions were extracted by constructing drug relationship network graph. Results A total of 120 patients with diabetes mellitus type 2 were included in this study,and 96 Chinese medicines were used in total. The top five ingredients of drug frequency were unprocessed Rehmanniae Radix, Coptidis Rhizoma, Anemarrhenae Rhizoma, corn stigma, and Salviae Miltiorrhizae Radix Et Rhizoma. The top five drug tastes were sweet, bitter, pungent, sour, and tasteless. The top five channel tropism frequencies were liver,lung, kidney, stomach, and spleen channels. The most common drug was unprocessed Gypsum Fibrosum-Anemarrhenae Rhizoma. The core prescription was unprocessed Rehmanniae Radix, Salviae Miltiorrhizae Radix Et Rhizoma, corn stigma,Coptidis Rhizoma, Anemarrhenae Rhizoma, Schisandrae Chinensis Fructus, unprocessed Gypsum Fibrosum, Puerariae Lobatae Radix. Conclusion Professor Feng is good at using replenishing the vital essence and removing heat drugs in the treatment of diabetes mellitus. The drug tastes are mostly sweet and bitter, Gypsum Fibrosum-Anemarrhenae Rhizoma are most often used together.更多还原